To our knowledge, there is only one study that an aromatase inhibitor, Letrozole
plus rFSH was used for ovarian stimulation.4 In the presented case series, we have shown that COH can be started at any time in a menstrual cycle in the case of emergency fertility preservation.
(1) There are three available AIs: anastrozole, letrozole
, and exemestane.
is one such oral nonsteroidal aromatase inhibitor which prevents the aromatase from producing estrogens by competitive, reversible binding to the heme of its cytochrome P450 unit [2, 3].
Six months of vitamin D at 30,000 IU per week proved safe and was associated with "less worsening" of musculoskeletal events and fewer overall adverse quality of life events in women starting adjuvant letrozole
(Femara) for hormone receptor--positive breast cancer, Dr.
All of the participants had received the aromatase inhibitors letrozole
or anastrozole, nearly half had received tamoxifen, and two-thirds had received chemotherapy.
NEW drug letrozole
cut the risk of breast cancer returning by one-fifth.
The FDA approved lapatinib in combination with letrozole
for the treatment of postmenopausal women with advanced breast cancer that is hormone receptor and HER2 positive and for whom hormonal therapy is indicated.
In the EGF30008 trial, a double-blind, placebo-controlled, first-line Phase III trial to explore the benefit of letrozole
with or without lapatinib, 1286 patients were randomly assigned to receive oncedaily treatment with letrozole
plus lapatinib or letrozole
The treatment, known as Letrozole
hormone therapy, cuts the supply of the hormone oestrogen which is needed for certain cancers to grow.
versus testosterone: a single-center pilot study of HIV-infected men who have sex with men on highly active anti-retroviral therapy (HAART) with hypoactive sexual desire disorder and raised estradiol levels
The greatest benefit was with the newest aromatase inhibitors, such as letrozole
(Femara) and anastrazole (Arimidex).