leukaemogenic

(redirected from leukemogenesis)
Also found in: Medical.

leukaemogenic

or

leukemogenic

adj
(Pathology) relating to the development of leukaemia, or causing leukaemia. Also: leucaemogenic
References in periodicals archive ?
R)-2-hydroxyglutarate is sufficientto promote leukemogenesis and its effects are reversible.
Ascorbate regulates hematopoietic stem cell function and leukemogenesis," Nature, 2017; DOI: 10.
Results: We described clonal evolution and how it changes our view on leukemogenesis, treatment responses, and disease relapse.
mir-196a HOXA9 Related to pediatric acute lymphoblastic leukemia and participation in myeloid differentiation mir-15 BCL2 Related to chronic lymphocytic leukemia mir-150 MYB Inhibition of leukemogenesis (*) Selected putative targets are predicted using Target scan and miRBase online websites Table 2: Expression levels of the selected miRNAs before and after in vitro culture MicroRNA Expression Expression Ratio of level in level in expressions Sample 1 Sample 2 in Sample 2 to Sample 1 mir-125a 2.
Moreover, in terms of the development of organs and tumors, RUNX1 is known to play an important role in hematopoiesis, neural development, and leukemogenesis (Speck and Gilliland, 2002; Yoshikawa et al.
It has been implicated in leukemogenesis by generation of fusion proteins that modulate the activity of transcription factors or kinases [3].
Biologically, the cytogenetic changes define the syndrome, and the molecular consequences of the chromosomal changes found in APL play a critical role in leukemogenesis.
Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis.
Rauch A et al; Leukemogenesis of Hydroxyurea in the treatment of SCA.
4,5) In addition, more than two gene alterations--including fusion genes, deletions and point mutations--were identified in clinical samples of AML patients, suggesting that multiple mutations are required for leukemogenesis, as it is the case with solid tumors.