leucodepleted

(redirected from leukodepleted)

leucodepleted

or

leukodepleted

adj
(Medicine) of or denoting blood from which the white cells have been removed
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
One donor of leukodepleted platelets, which were transfused 12 years before clinical onset in the recipient, died in 2013 at 76 years of age, and the diagnoses on the death certificate were vascular dementia and bladder cancer.
transfusion to donors donors donors onset, y alive dead 3 RBC LD 4 4 0 6 RBC LD 6 6 0 7 RBC LD 19 19 0 9 RBC LD 3 3 0 10 RBC LD 4 4 0 12 Whole blood LD; RBC 2; 27; 42 2; 27; 41 0; 0; 1 LD; platelets LD * LD, leukodepleted; RBC, red blood cells.
The Trial to Reduce Alloimmunization to Platelets (TRAP), a study conducted in patients with AML receiving standard induction chemotherapy, showed that 16 percent of patients receiving non-leukocyte-reduced products met the criteria for refractoriness as opposed to 7-10 percent of patients receiving some form of leukodepleted product, with no significant difference between single donors and pooled random donor platelets.
Note: Where indicated and if available, prestorage leukodepleted products obtained from blood services are preferable to bedside leukodepletion; prestorage leukodepletion removes leucocytes prior to release of cytokines, which are responsible for adverse effects such as febrile non-haemolytic reactions.
Random-donor platelet concentrates are prepared from buffy coats and are not usually leukodepleted. Single donor (apheresis) platelet concentrates are routinely leukodepleted; the indications for this product are similar to those mentioned above for leukodepleted products.
Before the 2U0Us only selected patients received leukodepleted transfusions for the prevention of HLA alloimmunization, cytomegalovirus (CMV) transmission (or reactivation), and febrile non-hemolytic transfusion reactions (FNHTR) due to cytokines or leukocyte antibodies present in the patient.
Comparison of RTCs that included patients transfused with leukodepleted and leukocyte-containing RBCs Study No.
In total, 13 RCTs on leukodepleted blood transfusions in different clinical settings evaluated postoperative infections as a primary or secondary endpoint (31-36), (40-46).