NextSource bought the rights to a brain cancer drug called lomustine
EORTC 26101 is an independent Phase III, multicenter, randomized, open-label trial, conducted by the European Organization for Research and Treatment of Cancer (EORTC), that evaluated the addition of Avastin to lomustine
chemotherapy in 432 patients with previously treated glioblastoma.
Prior to 1999, nitrosourea-based combinations were the most commonly used chemotherapeutic agents in GBM, among which carmustine and lomustine
were the most active agents.
The aim of this study was to report the first case of FCTL in Brazil and to describe the clinical signs, diagnostic procedure and therapeutic effect using lomustine
and prednisolone of this rare and aggressive form of cutaneous lymphoma in cats.
Phase II trial of lomustine
plus temozolomide chemotherapy in addition to radiotherapy in newly diagnosed glioblastoma: UKT-03.
There are currently 75 drugs associated with pulmonary fibrosis, including amiodarone, bleomycin, busulfan, carmustine, lomustine
The bird showed partial response to treatment with chlorambucil, lomustine
, prednisone, L-asparaginase, and whole-body radiation, with neither evidence of adverse effects nor clinical signs of disease.
Previous case reports have described treatment with vincristine, lomustine
, and prednisone, (4) vincristine alone, (12) and procarbazine, CCNU, and vincristine.
The patient underwent surgery and radiation therapy, followed by first line chemotherapy with temozolomide and second line chemotherapy with lomustine
, vincristine, and procarbazin, due to disease progression.
Studies have found that about 50 percent of cats with cancerous MCTs respond to treatment with a chemotherapy drug called lomustine
When a fourth growth appeared in a recent MRI, they switched her treatment to a drug called lomustine
(CCNU), which she started on Thursday.
An oligodendroglioma with those molecular alterations has a better response to PCV (procarbazine hydrochloride, lomustine
[CCNU; CeeNU], and vincristine sulfate) chemotherapy.