voluntarily recalls Losartan
Potassium and Ezetimibe in prescription drug bottles in the U.S.
Following several (https://www.ibtimes.com/blood-pressure-medication-recall-2019-expanded-recall-issued-cancer-causing-impurity-2800134) recalls for blood pressure medication over the last few months because of a cancer-causing impurity, (https://www.fda.gov/safety/recalls-market-withdrawals-safety-alerts/macleods-pharmaceutical-limited-issues-voluntary-nationwide-consumer-level-recall-losartan-potassium) Macleods Pharmaceuticals Limited has issued a recall for 32 lots of Losartan
Potassium USP tablets and Losartan
Potassium/Hydrochlorothiazide combination tablets for an impurity that could cause cancer.
The rats were randomly divided into four groups (n = 8): negative control group (distilled water), TAA (positive control) group, candesartan cilexetil group (0.2 mg/kg/day) (Gaur & Kumar, 2011), and losartan
potassium group (7.5 mg/kg/day) (Croquet et al., 2002).
M2 PHARMA-May 15, 2019-Vivimed Life Sciences Issues Voluntary Nationwide Recall of Losartan
Potassium 25 mg, 50 mg and 100 mg Tablets, USP Due to the Detection of Trace Amounts of N-Nitroso-N-methyl-4-aminobutyric acid Impurity
Nitrosamines have recently re-surfaced in the pharmaceutical world due to FDA and other international agencies finding traces of these compounds in the angiotensin II receptor blockers (ARBs), commonly known as the "sartans." The drugs involved are Valsartan, Losartan
, Irbesartan, Azilsartan, Olmesartan, Eprosartan, Candesartan and Telmisartan.
M2 EQUITYBITES-April 29, 2019-Teva Pharmaceuticals USA recalls 35 lots of bulk Losartan
Potassium USP Tablets
Of the other three options, losartan
offers the added benefit of lowering uric acid levels.
A company that supplies and sells products containing losartan
has been ordered to stop doing so, says Health director-general Datuk Noor Hisham Abdullah.
On the last day of August, one lot of Camber Pharmaceuticals' Montelukast Sodium Tablets were voluntarily recalled because their sealed bottles were labeled as such but instead contained a different drug: Losartan
Bottles labeled as containing 30 tablets of 10-milligram montelukast sodium tablets instead contain 90 tablets of losartan
"Following a recall of valsartan around the globe, many people taking other forms of hypertension medication, such as losartan
, are unsure whether their medication is affected," said Ms Ruff, the marketing and communication head of MyTherapy, a health app of Smart Patient.
It is known that in the combination of omeprazole and losartan
, omeprazole acts as an inhibitor of hepatic drug metabolizing enzyme and increases the level and effect of losartan