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Related to lovastatin: simvastatin


A statin drug, C24H36O5, that blocks the body's synthesis of cholesterol and is used to lower cholesterol (especially LDL) levels and to reduce the risk of heart attack and stroke in individuals with elevated risk.

[lo-, of unknown origin + -vastatin, statin suffix; see pravastatin.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Pharmacology) a drug, of the statin class, used to reduce cholesterol. Formula: C24H36O5
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌloʊ vəˈstæt n)
a drug that reduces the levels of fats in the blood by altering the enzyme activity in the liver that produces lipids.
[1985–90; of undetermined orig.]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.lovastatin - an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate
lipid-lowering medication, lipid-lowering medicine, statin, statin drug - a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


n lovastatina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
In 1987, lovastatin, the first statin drug, was approved by the Food and Drug Administration (FDA) and was released for marketing.
There is another medication which is made by lovastatin, used to lower LDL cholesterol.
Research shows that red yeast rice, which contains naturally-occurring lovastatin compounds, can lower "bad" LDL cholesterol.
A Red yeast rice has been used in Chinese medicine for centuries, and contains several substances that are known to inhibit cholesterol synthesis--in fact one of these forms the basis of lovastatin (Mevacor).
(30) to determine the mean percent change from baseline for lovastatin (10, 20, 40, and 80 mg), pravastatin (10, 20, and 40 mg), simvastatin (5, 10, 20, 40, and 80 mg), atorvastatin (10, 20, 40, and 80 mg), fluvastatin (20 and 40 mg), rosuvastatin (5, 10, 20, and 40 mg), and ezetimibe (10 mg; all daily doses).
Aspirin and statins (lovastatin and simvastatin) were the most frequently used drugs in the management of stroke.
The studies which were included in this meta-analysis should meet the following criteria: (1) the design of studies should be controlled strictly, including case-control studies, cohort studies, and RCTs; (2) no prior diagnosis of any cancer prior to the date of cancer diagnosis; (3) studies should specific one or more types of statins, including rosuvastatin, atorvastatin, simvastatin, pravastatin, fluvastatin, cerivastatin, and lovastatin; (4) studies should be designed to evaluate the impact of statins on the risk of cancers with T2DM; (5) studies should have provided sufficient information to calculate odds ratios (ORs) and 95% confidence intervals (CIs).
to determine levels of monacolin K, the same ingredient found in lovastatin (Mevacor), a prescription statin drug that lowers cholesterol.
As a consequence, areas under the curve for simvastatin and lovastatin skyrocket when those statins are given with some protease inhibitors, placing patients at increased risk for myopathy, including rhabdomyolysis.
The red yeast rice provided 3 mg per day of monacolin K (lovastatin), which is a lower dose than that used in previous studies of red yeast rice.
"This is an issue only for lovastatin and simvastatin and is only problematic at the highest dosages," says Dr.
One study found that pu-erh tea contains a microbial source of lovastatin. Lovastatin isn't present in the tea before it's stored, but it develops during the aging and natural fermentation process.