to determine levels of monacolin K, the same ingredient found in lovastatin
(Mevacor), a prescription statin drug that lowers cholesterol.
As a consequence, areas under the curve for simvastatin and lovastatin
skyrocket when those statins are given with some protease inhibitors, placing patients at increased risk for myopathy, including rhabdomyolysis.
has been identified as the most predominant monacolin in red yeast rice, although up to 10 distinct monacolins have been found in some products.
This is an issue only for lovastatin
and simvastatin and is only problematic at the highest dosages," says Dr.
isn't present in the tea before it's stored, but it develops during the aging and natural fermentation process.
formulations took the top two spots, with Vytorin at the top of the brand list and lovastatin
, the generic for Merck's Mevacor, at the top of the generics list.
The risk with fluvastatin and lovastatin
was similar to pravastatin.
However, the amounts of lovastatin
compounds in these three products were found to be as much as 88% higher to 33% lower than in 2011--suggesting they may now be more, or less, effective, respectively, than before.
A high mean daily dosage of lovastatin
was positively associated with the development of dementia, possibly because lovastatin
is a lipophilic statin while the anti-inflammatory cholesterol lowering effect of lovastatin
is not comparable to that of atorvastatin and simvastatin.
Colombia has adopted an essential drugs list into the Plan Obligatorio de Salud (Mandatory Health Plan, POS); initially it included three generic agents for dyslipidemia management: lovastatin
, gemfibrozil, and cholestyramine (11).
Washington, December 28 ( ANI ): It has been found that adding lovastatin
, a widely used cholesterol-lowering drug, to traditional antimalarial treatment decreases neuroinflammation and protects against cognitive impairment in a mouse model of cerebral malaria.
According to yet another report "The drug known as lovastatin
(which is known by several brand names, including Mevacor [lovastatin
]) can cause muscle weakness in rare cases.