Prolactin (PRL) is a luteotropic
and pleiotropic hormone involved in many physiological functions, such as angiogenesis, the immune response, osmoregulation, reproductive behavior and lactogenesis.
GCs were cultured in a dose-dependent and time-dependent manner with DE-T1, proliferation of GCs was determined by Cell Counting Kit-8 assay, and mRNA levels of insulin-like growth factor 1 receptor (IGF-1R), luteotropic
hormone receptor (LHR), follicle-stimulating hormone receptor (FSHR), LHR, and CYP19A1 (aromatase) were determined by quantitative polymerase chain reaction.
The corpus luteum (CL) is a transient endocrine gland that biosynthesizes steroids under the control of luteotropic
(14) TSH possess a luteotropic
activity and reach one fifth of the biological activity of human chorionic gonadotropin (hCG) (15).
hormone which is called as lactotropic hormone stimulates milk production that is the basic function of prolactin in females (Guyton, 2001).
Tumor necrosis factor-alpha has both luteotropic
and luteolytic functions .
We also found that LPA did not express only direct luteotropic
action  but also indirect luteoprotective role inhibiting cytokine mediated regression of the bovine CL .
However during infection, bacterial toxin binds directly to uterine epithelial and stromal cell to stimulate the release of prostaglandin [E.sub.2] which is luteotropic
and may prevent luteolysis (Bogan et al., 2008).
In reproduction, PRL can have a luteotropic
or luteolytic action, depending on the stage of the reproductive cycle.
Ghrelin affects the release of luteolytic and luteotropic
factors in human luteal cells.
Finally, secondary CL begin to develop around the time the primary CL begins to regress and these are quite resistant to luteolysis due to the heavy luteotropic
supported by LH and eCG.
Prolactin, the lactogenic or luteotropic
hormone (LTH), is vital for the proper development of lactation in horses.