Nietzsche as an evolutionist I shall have occasion to define and discuss in the course of these notes (see Notes on Chapter LVI
., par.10, and on Chapter LVII.).
In some studies, different clinicopathologic features, such as T4 tumor, low count lymph node evaluation, high-grade tumor, male gender, bowel obstruction, presence of LVI
or PNI, and high preoperative CEA, have been linked to a high possibility of death and recurrence (6-17).
Breast cancer prognosis is related to different factors including age, tumor size, grade, histologic type, lymphatic vessel invasion (LVI
), lymph node metastasis, and expression of hormone receptors., Among them, LVI
and lymph node metastasis are the main prognostic factors in patient's survival., Furthermore, LVI
plays a critical rule in cancer metastasis. It is considered as an independent prognostic factor in lymph node-negative patients with mortality of breast cancer increases from 29% to 53% in node-negative patients with LVI
.,, This emphasizes the importance of correct detection of LVI
is a well-known risk factor for LR and DM.7 After multivariate analysis, LVI
proved to be the only independent factor predictive of recurrence in this study (p=0.004).
Pathological findings included the pathological T stage (<T3 or [greater than or equal to]T3), LVI
, carcinoma in situ (CIS), and tumor grade (G1/2 vs.
Data regarding the prognostic factors including patient's age, body mass index (BMI), TS (cm), ki-67 score (%), ER, PR, c-erb-2 receptor status, molecular classification (MC) (LA, LB, Her-2 and TNBC) data, histopathological diagnosis, nuclear grade status (Modified Bloom Richardson), mALNscount (pN1, pN2, pN3), LVI
, and the methods of operation were recorded.
Pathological features, including tumor size (maximum diameter in centimeters), tumor border configuration (expanding or infiltrating), WHO histological grade , pTNM stage , TB, LVI
, grading based on the counting of PDC , and the presence of lymph node micrometastases (MM) , were available in all cases.
That's why the USTERA(r) LVI
930 length tester, for example, with its speed of 50 samples per hour, still has its fans.
Patients with high-risk Stage II disease were defined as those with poor prognostic features, including: (1) T4 tumors (IIB/IIC), (2) poorly tumor differentiation (TD), (3) lymphovascular invasion (LVI
), (4) peripheral nerve invasion, (5) bowel obstruction or lesions with localized perforation, (6) uncertain or positive margins (UPM), and (7) inadequately sampled LNs (<12).
The significance of spermatic cord LVI
in the absence of cord soft tissue invasion has not been evaluated, to our knowledge, in testicular germ cell tumors.
Prognostic significance for histologic grading as well as lymphovascular invasion (LVI
) is limited to node-negative breast cancers, with borderline tumor sizes.7