(NSLA), a rare benign salivary gland tumor, is included in the World Health Organization's classification of 2005 (1).
Although they are found in a variety of lesions, primary neoplastic lesions with predominant sebaceous component, such as sebaceous adenoma and sebaceous lymphadenoma
, are very rare and account for less than 1% of salivary gland tumors .
Immunohistochemical comparison of cutaneous lymphadenoma
, trichoblastoma, and basal cell carcinoma: support for classification of lymphadenoma
as a variant of trichoblastoma.
Benign lesions other than pleomorphic adenoma and Warthin tumor included oncocytic adenomas, lipomas, lipomatosis, basal cell adenoma, nonsebaceous lymphadenoma
, branchiogenic cyst, and chronic inflammation.
, angiomyofibroblastoma, cellular angiofibroma, sarcomas, angiomyxoma and dermatofibrosarcoma protuberans are other differential diagnosis.
The diagnosis of GD should be distinguished from leukemia, lymphadenoma
, multiple myeloma, and other diseases.[sup]
There is a bimodal age distribution with peaks in the third and seventh to eighth decades.123 Clinically the symptoms vary from an indolent slow-growing painless asymptomatic mass to a painful rapidly progressing swelling accompanied by facial paralysis.45 If the sebaceous tumor is associated with lymphatic structures it will be named lymphadenoma
Other benign tumours included 3 cases (1.85%) of lipomas all seen in the parotid, and 1 case (0.61%) each of haemangioma, basal cell adenoma, oncocytoma, myoepithelioma and sebaceous lymphadenoma
(Table 1 and Table 3).
Similarly trichoepithelomas18, and cutaneous lymphadenoma
shows variable degree of positivity19.