Other haematological abnormalities detected were leucopenia in 2% of cases, neutropenia in 3% of cases, lymphocytopenia
in 18 % of cases and thrombocytopenia in 9 % of cases at the time of presentation.
and neutrophil-lymphocyte count ratio predict bacteremia better than conventional infection markers in an emergency care unit.
In patients with advanced cancer, tumor prognosis is strongly correlated with leukocytosis, lymphocytopenia
, and CRP (18).
In contrast, slow lymphocytopenia
observed in our tilapias could be correlated with a compensatory intercellular regulation (Pickering, 1998).
Systemic inflammation has been associated with neutrophilia and lymphocytopenia
, thus, elevated NLR value (6, 16).
(49-52) Germline GATA2 mutation is associated with a broad spectrum of phenotypes, encompassing hematologic disease such as AML and MDS; infection characterized by viral, mycobacterial, and fungal infection; immunodeficiency with monocytopenia; B- and NK-cell lymphocytopenia
; skin conditions with warts and panniculitis; pulmonary disorder; and vascular/lymphatic dysfunction.
There are some studies indicating that the changes in the rate of circulating leukocytes can recognize the bacteremia at an early stage.3 Firstly, Zahorec and colleagues indicated that lymphocytopenia
is correlated with the severity of sepsis in oncology ICU, therefore they claimed NLCR could be a marker of infection.17 Then Wyllie and colleagues showed the significance of NLCR in predicting bacteremia compared to lymphocytopenia
or CRP.18 Various studies have been performed for determination of the optimal NLCR cut-off value based upon these findings, but obtained different cut-off value for sepsis and bacteremia.
is an important feature of H7N9 infection., The lymphocyte count in our patient was only 0.06 x 109/L with a significant reduction, which is rarely seen in H7N9-infected patients.
cases Serum creatine kinase Elevated 7 Cardiac troponin Elevated 2 Erythrocyte sedimentation Elevated 5 rate and C-reactive protein Full blood count Lymphocytopenia
6 Serum albumin Decreased 5 Alanine aminotransferase Elevated 5 and aspartate aminotransferase Serum creatinine Elevated 2 Urinary protein Elevated 3 Nerve conduction studies, Myopathy, axonal 6 electromyography neuropathy Brain radiologic imaging Cerebral lesions 2 Cardiac magnetic Biventricular 1 resonance imaging dysfunction Small subunit rRNA A.
It is the exhaustion of T cells which results in immunosuppression [19,20] In terms of the adaptive immune response, there is a relative lymphocytopenia
and an increase in the proportion of T helper type 2 cells, which also predisposes to immunosuppression.
 In an emergency care setting, both lymphocytopenia
and neutrophil-lymphocyte count ratio are better predictors of bacteremia than routine parameters such as CRP level, white blood cell count, and neutrophil count.
For example, it was shown that hypoalbuminemia and lymphocytopenia
are both independent predictors of fixation failure in nondisplaced femoral neck fractures ; therefore correction of such laboratory values may theoretically decrease failure and therefore reoperation and nonunion rates.