papulosis (LyP) is a rare cutaneous condition characterized by chronic, recurrent, and self-regressing papulonodular skin eruptions.
Other types of lymphoproliferative processes such as primary lung plasmacytoma and lymphomatoid
granulomatosis account for a good proportion of the remaining PPL .
Such NK-cell lymphoproliferative disorders of the GI tract have been reported as lymphomatoid
gastropathy and NK-cell enteropathy, representing the same disease.
The first group consists of CD30+ T-cell lymphoproliferative disorders, which include primary cutaneous ALCL (PC-ALCL)--which may be either anaplastic lymphoma kinase (ALK)-positive or ALK-negative--at the malignant end, and the morphologically and immunohistochemically identical lymphomatoid
papulosis (LyP), at the benign end of the spectrum.
"There are reports about T-cell receptor clonality in PL lesions and its similarity and association with lymphomatoid
papulosis and mycosis fungoides, and the presence of CD30-positive and CD7 deletions," she said.
papulosis (LyP) is a benign papulonodular skin eruption with histologic features of malignant lymphoma.
Zamkoff, "Hypercalcemia with excess serum 1,25 dihydroxy vitamin D in lymphomatoid
granulomatosis/angiocentric lymphoma," American Journal of the Medical Sciences, vol.
Even though lymphomatoid
granulomatosis is also in the differential diagnosis with angiocentric and angiodestructive EBV+ lymphoma involving extranodal sites, it tends to have polymorphous lymphoid infiltrates and more prominent blood vessel wall invasion and occurs in adults and immunodeficient children.
Indeed, research has shown that EBV infection is associated with a number of diseases, including infectious mononucleosis, lymphomatoid
granulomatosis, Hodgkin's lymphoma, Burkitt's lymphoma, gastric cancer, NPC, and multiple sclerosis.
except for stage IA disease and in lymphomatoid
Cryptogenic organizing pneumonia Invasive pulmonary fungal infections Paracoccidioidomycosis Pneumocystis pneumonia Tuberculosis Community-acquired pneumonia Lymphomatoid
granulomatosis Granulomatosis with polyangiitis Lipoid pneumonia and sarcoidosis Pulmonary neoplasms and infarction Following radiation therapy Following radiofrequency ablation of pulmonary malignancies High-risk ethnicity (%) HTN/HTN medications (%) HDL Cholesterol <35 and/or Triglyceride >250 (%) PCOS (%) History of CVD (%)