lysolecithin


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lysolecithin

(ˌlaɪsəˈlɛsɪθɪn)
n
(Biochemistry) any compound of lecithin produced by the removal of one of the fatty acid groups by hydrolysis
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
References in periodicals archive ?
This is the probable reason for the accumulation of free fatty acids and lysolecithin at high concentrations.
On the one hand, emulsifiers (lysophospholipids, lysolecithin, bile salts, or sodium stearoyl-2-lactylate) were used to increase the lipid digestibility because they increased the active surface of lipid droplets and promote incorporation of fatty acids into micelles [7,11,12].
One model used the ingested toxin cuprizone and the other used injected lysolecithin to achieve demyelination of CNS neurons and spinal nerve axons, respectively.
Blakemore, "Remyelination of mouse spinal cord axons demyelinated by local injection of lysolecithin," Journal of Neurocytology, vol.
Among these, it is possible to highlight the chemically induced CNS lesions, such as those generated with cuprizone feeding, ethidium bromide injection, and lysolecithin, or the experimental autoimmune encephalomyelitis (EAE) model, widely used in drug screening as it most faithfully represents the pathology seen in MS [184].
This decrease may be due to enhanced activity of LCAT (Lysolecithin Acyl Transferase) which also causes hypertriglyceridemia.
Drugs such as cuprizone and lysolecithin are frequently used to model multiple sclerosis [9], as these agents elicit partial demyelination when injected at specific sites in the spinal cord.
Regurgitation of duodenal contents, including alkaline pancreatic-duodenal secretions, bile salts, and lysolecithin into the gastric cavity may disrupt the gastric mucosa barrier and damage the mucosa epithelium.[sup][15] Excessive DGR results in accelerated regeneration of epithelium with histological appearance of foveolar hyperplasia and expansion of the smooth muscle fiber in the mucosa.[sup][16],[17] Patients with DGR had higher intensity of gastric mucosal inflammation.[sup][18],[19],[20] Matsuhisa and Tsukui also showed that high concentrations of bile acids were shown to have an effect on the progression of intestinal metaplasia in H.
Lysolecithin is generated in LDL particle as a result of the lipid peroxidation, and the concentration of esterified cholesterol is reduced, a number of lipid-derived oxidation products are formed, including lipid hydroperoxides, and specific products of linoleate and arachidonate oxidation are formed, including 9-hydroxy-10,12-octadecadienoic acid (9-HODE) and F2-isoprostanes [70,71].
The term "phospholipase B" was first described by Contardi and Ercoli (1) in 1933 as lecithase B, which attacked an acyl--ester bond of lysolecithin and produced one mole each of fatty acid and glycerophosphocholine (GPC).