Release date- 25072019 - Researchers publish results on organ-specific properties of macrophages
in the Nature Communications journal.
have critical roles in inflammatory response by phagocytosis or producing inflammatory mediators such as nitric oxide (NO) and pro-inflammatory cytokines such as interleukin (IL)-1[beta], IL-6, and tumor necrosis factor-[alpha] (TNF-[alpha]).
are distributed in various kinds of tissue and play an important role in many biological processes such as development, homeostasis, tissue repair, and immune response., Heterogeneity and plasticity are key features of the macrophage
lineage., These cells can adapt and respond to microenvironmental stimulation by altering their gene expression profile, metabolism, and function; this phenomenon is called 'macrophage
display a continuous spectrum of activation states, the two extremes of which are classically referred to as activated macrophages
(CAM or M1) and alternatively activated macrophages
(AAM or M2).
are the possible sources of these cytokines/chemokines.
are a type of white blood cell in the body's immune system.
17, 2018 (HealthDay News) -- Electronic cigarette (e-cigarette) vapor condensate (ECVC) is significantly more toxic to alveolar macrophages
than e-cigarette liquid (ECL), according to a study published online Aug.
pisiformis, quantification of macrophages
, lymphocytes, and eosinophils and measured of the total area of granulomas.
The vitamin D3-binding protein (Gc protein)-derived macrophage
activating factor (GcMAF) activates tumoricidal macrophages
against a variety of cancers indiscriminately.
Accumulation of cholesterol esters in macrophages
is a hallmark of foam cell formation, which depends on the uptake of oxidized low-density lipoprotein (ox-LDL) via CD36 .
Quantification of tissue uptake of iron nanoparticles and deposition in macrophages
is conventionally performed using region of interest (ROI) analysis of MRI images .
As a type of antigen-presenting cell, macrophages
have been found to regulate implanted biological materials during the tissue repair process .