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Related to macular dystrophy: macular corneal dystrophy


 (dĭs′trə-fē) also dys·tro·phi·a (dĭ-strō′fē-ə)
1. Any of various unrelated, noninfectious, often genetic disorders characterized by progressive deterioration or structural alteration of a body part.
2. A degenerative disorder caused by inadequate or defective nutrition. No longer in scientific use.
3. Ecology The condition of being dystrophic.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(ˈdɪstrəfɪ) or


1. (Pathology) any of various bodily disorders, characterized by wasting of tissues. See also muscular dystrophy
2. (Environmental Science) ecology a condition of lake water when it is too acidic and poor in oxygen to support life, resulting from excessive humus content
[C19: New Latin dystrophia, from dys- + Greek trophē food]
dystrophic adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˈdɪs trə fi)

also dys•tro•phi•a

(dɪˈstroʊ fi ə)

1. faulty or inadequate nutrition or development.
2. any of a number of disorders characterized by weakening, degeneration, or abnormal development of muscle.
[1885–90; dys- + -trophy]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

dystrophy, dystrophia

any of various diseases characterized by weakening or defective function of the process of nutrition, resulting in degeneration of the muscles. See also food and nutrition. — dystrophic, adj.
See also: Disease and Illness
poor or inadequate nutrition or growth. See also disease and illness.
See also: Food and Nutrition
-Ologies & -Isms. Copyright 2008 The Gale Group, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.dystrophy - any of several hereditary diseases of the muscular system characterized by weakness and wasting of skeletal muscles
Becker muscular dystrophy - a form of muscular dystrophy that sets in in adolescence or adulthood and progresses slowly but will affect all voluntary muscles; characterized by generalized weakness and muscle wasting that affects limb and trunk muscles first; similar to Duchenne's muscular dystrophy but less severe; inheritance is X-linked recessive (carried by females but affecting only males)
distal muscular dystrophy - a form of muscular dystrophy that sets in between 40 and 60 years of age and is characterized by weakness and wasting of the muscles of the hands and forearms and lower legs; inheritance is autosomal dominant
Duchenne's muscular dystrophy, pseudohypertrophic dystrophy - the most common form of muscular dystrophy; inheritance is X-linked recessive (carried by females but affecting only males)
limb-girdle muscular dystrophy - an autosomal recessive form of muscular dystrophy that appears anywhere from late childhood to middle age; characterized by progressive muscular weakness beginning either in the shoulder or pelvic girdle; usually progresses slowly with cardiopulmonary complications in the later stages
myotonia atrophica, myotonic dystrophy, myotonic muscular dystrophy, Steinert's disease - a severe form of muscular dystrophy marked by generalized weakness and muscular wasting that affects the face and feet and hands and neck; difficult speech and difficulty with the hands that spreads to the arms and shoulders and legs and hips; the onset can be any time from birth to middle age and the progression is slow; inheritance is autosomal dominant
oculopharyngeal muscular dystrophy - a form of muscular dystrophy that usually begins between early adulthood and middle age and first affects muscles of the eyelid and throat; progresses slowly with swallowing problems common as the disease progresses; inheritance is autosomal dominant
2.dystrophy - any degenerative disorder resulting from inadequate or faulty nutrition
degenerative disorder - condition leading to progressive loss of function
osteodystrophy - defective bone development; usually attributable to renal disease or to disturbances in calcium and phosphorus metabolism
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.


nDystrophie f, → Ernährungsstörung f
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007


, dystrophia
n. distrofia.
1. anomalía causada por desnutrición;
2. desarrollo defectuoso o de malformación.
English-Spanish Medical Dictionary © Farlex 2012


n distrofia; reflex sympathetic — (ant) síndrome m de dolor regional complejo, distrofia simpática refleja (ant)
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Evie was 11 when she began to have trouble with her eyesight and was diagnosed with Stargardt's macular dystrophy two years ago, a condition where her sight progressively gets worse.
It may also be referred to as Stargardt macular dystrophy or juvenile macular degeneration and affects approximately 1 in 8,000 - 10,000 individuals worldwide.
2 cases showed "hypofluorescent spot surrounded by hyperfluorescence" typical of Adult-onset Foveo Macular Dystrophy. All these cases were diagnosed clinically as macular dystrophies, but FA categorized them into specific entities.
In literature also mostly reported corneal dystrophies are bilateral.4 According to the French National Waiting List, dystrophies were the third most common indication for penetrating keratoplasty (PKP) and were divided into Fuchs dystrophy (65%), Lattice dystrophy (10%), Granular dystrophy (4%), Macular dystrophy (2%), and others (20%).5
(10) identified a homozygous frame-shifting mutation, c.601delG, p.Lys203Argfs*28, in RP1L1 in a consanguineous family with RP, while various mutations in this gene had been reported to be associated with occult macular dystrophy (OCMD).
In the preliminary report, no signs of negative proliferation, tumor formation, ectopic tissue development, or rejection were observed in 4 months of follow-up after subretinal application in one patient with Stargardt macular dystrophy and one patient with dry-type age-related macular degeneration (AMD).
Mutations in ABCA4 gene are known to cause Stargardt disease (STGD) which is the most frequent macular dystrophy [7] and typically presents with central macular atrophy and yellow-white dots at the posterior pole, primarily at the level of the RPE.
Gwynfor is a keen rock climber who competed in the world championships after losing his central vision due to macular dystrophy.
The two types of MD discussed in this article are Stargardt's macular dystrophy, which is known as the most familiar pediatric form, and dry age-related MD.
Until recently, peribulbar injections of amino acid taurine (one of the most abundant amino acids in mammalian tissues [20, 21]) were used in the former SU as a preparation named Taufon in elderly patients for prophylactic purposes as well as for the treatment of macular dystrophy associated with atherosclerosis [22], while hematomas were observed as complications.
Guide Dogs representative Vicky has macular dystrophy, a rare genetic eye disorder that causes sight loss, and lost all useful vision four years ago.
CHA Biotech Co., Ltd., the sponsor company of this clinical study, is planning to get approval from the Korean Ministry of Food and Drug Safety to carry out phase II clinical trials with Stargardt's macular dystrophy this year and to continue dose escalation with the age-related macular degeneration trial.

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