Lichenoid drug eruptions initially present as itchy small pink macules
that gradually progress to become firm violaceous, flat-topped, polygonal and scaly papules (Fig.
There were numerous adenoma sebaseum on her face (Fig-1), periungual fibromas (without trauma anamnesis) around the toenails (Fig-2), forehead plaques (Fig-3), Shagreen patches around the lumbar region, hypomelanotic macules
on the back.
Le sol et les murs sont macules
de sang et cribles de balles.
Amalgam tattoos are twice as common as melanotic macules
and ten times as common as oral nevi.
The original description of McCune-Albright syndrome (MAS) included diffuse fibrous dysplasia, cafe-au-lait macules
, and precocious puberty (1,2).
The other patient (Figure, panel C) displayed 56 macules
with 1 pruritic central vesicle.
Abstract: Neurofibromatosis 1 (NF1) is a multisystem genetic disorder that primarily affects the skin (freckling and cafe-au-lait macules
), nervous system (neurofibromas, optic gliomas, and learning disabilities), and skeletal system (pseudoarthroses).
A 53 year-old male patient, with diabetes which is under control with metformina and glibenclamida, presented macules
with absence of pigment compatible with vitiligo 10 years ego.
An 11-year-old girl presented with a 6-month history of weight loss, fatigue, loss of appetite, hyperpigmented macules
, general body swelling and chronic diarrhoea.
Ventral forewing duller than dorsum, distinctly brown caudad of [CuA.sub.2]; white macules
of dorsum repeated with additional narrow white macules
in [R.sub.1]-[R.sub.2] extending just distad of distal end of macule
in discal cell and in Sc-[R.sub.1], from mid-macule in [R.sub.1]-[R.sub.2] to well distad of distal end of that macule
roughly aligned with white macule
in discal cell; pale blue macule
at base of costa; postbasal band faint, most prominent in discal cell; thin line of pale blue scales at distal end of discal cell; submarginal pale blue macules
somewhat more prominent than on dorsum, that in [CuA.sub.2]-2A doubled; pale blue macule
in anal cell as on dorsum.
These slowly resolve leaving atrophic brown macules
. Granuloma annulare is a harmless self limiting condition that appears as single or multiple pink purplish annular lesions, most commonly on the hands.
This case illustrates the classic findings of carbon pigment deposition around terminal bronchioles, dust macules
, and mixed dust fibrosis.