major histocompatibility complex


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Related to major histocompatibility complex: human leukocyte antigen

major histocompatibility complex

n. Abbr. MHC
A group of genes in humans and most other vertebrates that code for cell-surface glycoproteins (called MHC molecules) which function in the immune system and also are principally responsible for determining tissue compatibility in transplants.

major histocompatibility complex

n
(Genetics) the full name for MHC

MHC

major histocompatibility complex: a group of genes that determine histocompatibility antigens, located in humans on the sixth chromosome. Compare HLA.
Translations
complexe majeur d’histocompatibilité
References in periodicals archive ?
7) Typical pathologic findings include endomysial mononuclear inflammatory infiltrate, which is CD8+ T cell predominant, major histocompatibility complex class 1 expression, and myofiber necrosis.
sup][5],[6],[7] [sz]2M has no transmembrane region and contains a distinctive molecular structure called a constant-1 Ig superfamily domain, sharing with other adaptive immune molecules including major histocompatibility complex (MHC) class I and class II.
Rapid assignment of the swine major histocompatibility complex (SLA) class I and II genotypes in Clawn miniature swine using PCR-SSP and PCR-RFLP methods.
Natural selection at major histocompatibility complex loci of vertebrates.
Genetic polymorphism of the swine major histocompatibility complex (SLA) class genes, sla-1, -2 and -3.
In contrast to the autoimmune diseases which are triggered by (auto)antigens with the involvement of major histocompatibility complex (MHC) class II-associated adaptive responsive genes in autoinflammatory diseases the cytokine and bacterial sensing genetic pathways are disturbed in response to an unknown cause.
The final chapter considers how new insights into the mechanisms of self tolerance, the biological role of the major histocompatibility complex, and the nature of antigen recognition by T cells have led to a deeper understanding of autoimmunity.
The study, which was published in Science Translational Medicine, detailed how researchers identified two specific single-nucleotide polymorphisms, also called SNPs, within the major histocompatibility complex in human DNA that are markers for either acute GVHD or disease-free survival.
Genetic relationship on the Guambiano, Paez, and Ingano Amerindians of southwest Colombia using major histocompatibility complex class II haplotypes and blood groups.
It has been reported that molecular defects in the factor VIII gene and the major histocompatibility complex molecules, especially FILA class II alleles, are associated with antibody formation.
Substantial evidence exists that mice and rats can distinguish urinary odors associated with differences in the major histocompatibility complex (MHC; Kavaliers et al.

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