In this latest work, however, Bilsland's team found that triclosan also inhibits an entirely different enzyme of the malaria parasite
, called DHFR.
The deadliest malaria parasite
needs two proteins to infect red blood cells and exit the cells after it multiplies, a finding that may provide researchers with potential new targets for drug development, according to researchers funded by the National Institutes of Health.
USA], Oct 27 (ANI): A team of researchers has recently discovered new targets for drug development against life-threatening malaria parasite
, which needs two proteins to infect red blood cells and exit after multiplying.
On a programmatic scale, a 10-fold increase in malaria cases was observed in KwaZulu-Natal, South Africa, subsequent to the re-emergence of pyrethroid-resistant Anopheles funestus mosquitoes and emergence of malaria parasite
drug resistance to sulfadoxine/pyrimethamine (8).
Researchers found that blocking the activity of an enzyme called NMT in the most common malaria parasite
prevents mice from showing symptoms and extends their lifespan, Science Daily reported.
Sanaria Inc, a company that develops and commercialises whole-parasite malaria vaccines, announced on Monday that a clinical trial of Sanaria PfSPZ (Plasmodium falciparum sporozoite) Vaccine to prevent malaria infections has shown that the vaccine provided protection against infection with malaria parasites
for at least 14 months in subjects who were exposed to Plasmodium falciparum parasites, the malaria parasite
that causes about 438,000 deaths and 214 million cases each year.
The white-tailed deer, maybe the best-studied wild animal in North America, carries a malaria parasite
that science has overlooked for decades.
We didn't know whether it was the malaria parasite
itself or the inflammatory reaction to malaria that was actually inhibiting the ability to develop protective immunity," Dr.
At least 200 fields were examined for malaria parasite
before reporting as negative.
Furthermore, the PCR had revolutionized the ability to detect sequences specific to each of the human malaria parasite
species, and with the development of highly sensitive molecular diagnostic assays, researchers were poised to transform perspectives regarding malaria epidemiology (13).
Mosquitoes become infected with the malaria parasite
when they bite an infected person.
The heat-seeking detector, which is coupled to an infrared imaging microscope, allowed the team to detect the earliest stages of the malaria parasite
in a single red blood cell.