Six renal biopsies were available in case groups--4 in the CGN group showed focal segmental glomerulosclerosis, IgA nephropathy (n=2) and mesangial capillary glomerulonephritis; 2 in the hypertensive nephropathy group showed malignant hypertension
, and 1 showed cortical necrosis.
Arthralgia was noted in 55.5% cases which is little higher than the result of North Indian study6 and lower than the finding of Krishnamurthy et al.10 Malignant hypertension
secondary to renal involvement develops in about 8% patients.16 None of our patients had malignant hypertension
The incidence of complications of the PKRP group was 38.8%; four patients had malignant hypertension
in perioperative period, and they were given obstruction relief and blood pressure lowering treatment; three patients had symptoms such as palpitation, short of breath, dyspnea and congestive heart failure and were sent to intensive care unit (ICU) for symptomatic treatment at the end of surgery; one patient had pulmonary edema and were given symptomatic treatment after stopping surgery; one patient felt cold because of excessive blood loss and had a low blood pressure, 80/50 mmHg, and therefore were given transfusion of 2U of blood.
The clinical suspicion was that of an ANCA vasculitis or anti-GBM disease, with a differential diagnosis that included complement mediated haemolytic uraemic syndrome (HUS), thrombotic thrombocytopaenic purpura (TTP), and malignant hypertension
Lone, "Recurrent malignant juxtaglomerular cell tumor: A rare cause of malignant hypertension
in a child," Journal of Indian Association of Pediatric Surgeons, vol.
Some patient-specific factors that may increase the propensity for hemolysis include, but are not limited to, hemolytic uremic syndrome, malignant hypertension
, some malignancies that predispose to microangiopathic hemolytic anemia, hypersplenism, hemolytic disorders (e.g.
is another cause of cardiac stress in renal patients.
However, our patient progressed from benign to malignant hypertension
, renal failure commonly supervened.
Instead, the dominant signs were transient malignant hypertension
, hearing loss, and slurred speech.
She also had malignant hypertension
. She was a nonsmoker with no exposure to occupational carcinogens and a negative familial history for renal malignancies; her body mass index was 28.7 kg/[m.sup.2].
The syndrome characterized by a sudden increase in systolic and diastolic BPs (equal to or greater than 180/120 mmHg) associated with acute end-organ damage that requires immediate management otherwise it might be life-threatening was defined as malignant hypertension