In mammary duct
ectasia (MDE), the periductal inflammation is the principal pathological expression.
Papillary breast lesions encompass a spectrum of masses, which pathologically demonstrate fronds attached to the inner mammary duct
wall by a fibrovascular core with both epithelial and myoepithelial cells.
Ultrasound of the breasts may reveal dilated subareolar ducts denoting mammary duct
ectasia and in some cases can pick up the papilloma.
Irrigation or visualization optics can then be introduced into the mammary duct
via the introduced cannula, allowing physicians to perform a variety of intraductal procedures with minimal or no discomfort for patients.
Mammastatin is detected in the mammary duct
epithelial cells of normal breast tissue, and it is secreted into the blood--but is not found in breast milk.
The remarkable similarity in the microscopic features of salivary duct carcinomas and mammary duct
carcinomas further raises questions as to whether these tumors share antigenic or hormonal features.
Microlobulation, a branching pattern or extensions along the ducts, indicates that the tumor is located within the mammary duct
, which increases the chances of malignancy.
The tiny slide-size model, dubbed 'breast on-a-chip' for its replication of the branching mammary duct
system, could help experts to test nanomedical approaches for the detection and treatment of breast cancer.
Furthermore, depending on their location in the mammary duct
system, papillary lesions may be solitary, centrally (subareolar) located or multifocal, and peripherally located within terminal duct-lobular units.