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Noun1.mastocyte - a large connective tissue cell that contains histamine and heparin and serotonin which are released in allergic reactions or in response to injury or inflammation
connective tissue - tissue of mesodermal origin consisting of e.g. collagen fibroblasts and fatty cells; supports organs and fills spaces between them and forms tendons and ligaments
somatic cell, vegetative cell - any of the cells of a plant or animal except the reproductive cells; a cell that does not participate in the production of gametes; "somatic cells are produced from preexisting cells";
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References in periodicals archive ?
These mediators are released after tissue injury, when there is an increase in arachidonic acid-derived eicosanoids such as prostaglandins and leukotrienes, which induce mastocyte degranulation.
Levi-Montalcini, "A proposed autacoid mechanism controlling mastocyte behaviour," Agents and Actions, vol.
Modern pharmacological research [34] suggests that by tonifying qi and strengthening exterior, Yupingfegn can boost immunity, improve allergic constitution, inhibit mastocyte release of bioactive substances, strengthen the T cell-mediated cellular immunity effect, increase the number of T cells, and improve lymphocyte transformation rate [35].
In experimental studies, platelet aggregation, mastocyte degranulation and histamine secretion have been shown to occur after trigeminal ganglion stimulation (2).
Furthermore, there was a significant reduction in mastocyte and eosinophil numbers in mucosa and lower levels of specific anti-H.
Previous research showed that the mechanism of carrageenan-evoked inflammation is that the external stimulus is devoured by mastocyte that leads to the degranulation of mastocyte and the releasing of inflammatory mediators [27].
Not only ligands, but also immunological host environments are decisive for mastocyte activity.
It turned out that, in allergic CD, keratinocytes secrete proinflammatory cytokines and chemokines that activate epidermal Langerhans cells and dermal vascular endothelial cells, which also express adhesion molecules and enable extravasation of the sensitized T cells (CD8, Tr1), mastocytes, basophils and immunocytes (19,20).
Neurons and mastocytes dump serotonin into my bloodstream.