mastocytosis


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Translations

mas·to·cy·to·sis

n. mastocitosis, mastocitos neoplásicos que aparecen en varios tejidos como urticaria pigmentosa.

mastocytosis

n mastocitosis f
References in periodicals archive ?
The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations.
Patients with hyperpigmented lesions should have the skin stroked firmly to elicit Darier's sign suggestive of cutaneous mastocytosis and a baseline serum tryptase level to rule out mastocytosis along with a lesional biopsy should be performed, if indicated.
The disease is usually diagnosed in pediatric patients and in the absence of clear evidence and family history of EB there are a few differential diagnosis regarding the skin lesions which must be excluded such as: Staphylococcal scalded skin syndrome, bullous impetigo, chemical burns, drug or viral-induced toxic epidermal necrolysis and bullous mastocytosis [5].
Finally, doctors diagnosed one of the rarest medical conditions in the UK - Diuse Cutaneous Mastocytosis or Masto for short.
Several studies so far have demonstrated that sevoflurane can be safely used in patients diagnosed to have mastocytosis (a group of rare disorders caused by the presence of too many mast cells) without triggering mast cell degranulation with release of histamine, prostaglandin, tryptase, and heparin [12].
The histopathologic diagnosis was a cutaneous mast cell tumor and disseminated mast cell disease, or mastocytosis. To the authors' knowledge, this is the first reported case of a cutaneous mast cell tumor and mastocytosis in a psittacine bird.
Mastocytosis can have multisystem involvement including the skin.
Other, less common disorders in this group include chronic neutrophilic leukemia (CNL), chronic eosinophilic leukemia (CEL), mastocytosis, and myeloproliferative neoplasm, unclassifiable (MPN,U).
Doctors treated the two-yearold's condition - diffuse cutaneous mastocytosis - with a treatment called Psoralen UVA.
Systemic mastocytosis is a rare disorder characterised by tissue infiltration of morphologically abnormal mast cells (1,2).
Blueprint Medicines is initially developing avapritinib for the treatment of advanced GIST, advanced systemic mastocytosis (SM), and indolent and smoldering SM.
kinase switch control inhibitor in clinical development for the treatment of KIT and/or PDGFR?-driven cancers, including gastrointestinal stromal tumors, or GIST, systemic mastocytosis, or SM, and other cancers.