mecamylamine


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Related to mecamylamine: Mecamylamine hydrochloride, Trimethaphan

mecamylamine

(ˌmɛkəˈmɪləˌmiːn)
n
(Pharmacology) a ganglion-blocking drug administered orally to lower high blood pressure. Formula: C11H21N
[C20: from me(thyl) + cam(phane) (a former name of bornane) + -yl + amine]
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References in periodicals archive ?
Gestational exposure of mice to secondhand cigarette smoke causes bronchopulmonary dysplasia blocked by the nicotinic receptor antagonist mecamylamine.
Other medications tested included atomoxetine, citalopram, dextromethorphan, levetiracetam, mecamylamine, omega-3 fatty acid, and secretin.
Cholinergic receptor blockade by scopolamine and mecamylamine exacerbates global cerebral ischemia induced memory dysfunction in C57BL/6 J mice.
This reduction in body weight was in agreement with that reported by study22 that showed that blocking nicotinic receptor by mecamylamine a nonselective nicotinic acetylcholine receptor antagonist present in brainstem would promote food intake by blocking dopaminergic pathway.
In most trials a combination of mecamylamine with nicotine patch has been found to be more effective than mecamylamine alone.
Reddy's packaged in single-dose vials Zoledronic Acid Injection, 4 mg (base)/5 ml, Agila Specialties packaged in single-dose vials Fluvoxamine Maleate Extended-Release Anchen Capsules, 100 mg, 150 mg Pharmaceuticals Esomeprazole Sodium for Injection, 20 mg Sun Pharma and 40 mg;,packaged in single-use vials Mecamylamine HydrochlorideTablets Nexgen LISP, 2.
Its product offering includes Chenoda, a chenodeoxycholic acid used for the treatment of patient suffering from gallstones and cerebrotendinous xanthomatosis (CTX), and Vecamyl, or mecamylamine tablets, for management of moderately severe to severe essential hypertension.
8) The learning ability of the rats infused with GGR-41 was remarkably reduced to the same extent as seen in the rats given mecamylamine, a nicotinic cholinergic receptor antagonist.
One RCT (N=48) comparing nicotine patches plus the nicotine antagonist mecamylamine with patches plus placebo found improved abstinence rates at 6 and 12 months; a larger RCT didn't support these findings.
Glick S, Visker K, Maisonneuve I (1996) An oral self-administration model of nicotine preference in rats: effects of mecamylamine.
Human laboratory studies have shown that mecamylamine, a nonselective nAChR antagonist approved for hypertension, can reduce alcohol preference and the stimulating effects of alcohol in healthy study participants (Blomqvist et al.