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Results: The main areas with increased brain activation were in frontal and parietal lobe, including left medial frontal gyrus, left inferior frontal gyrus, right middle frontal gyrus, right postcentral gyrus, and inferior parietal lobule in patients after CRT, yet no decreased brain activation was found.
Consistent findings have been reported in healthy and clinical populations, describing the increase in the BOLD response when aversive affective faces are compared to neutral faces, mainly in the amygdala; frontal regions such as the superior frontal gyrus, medial frontal gyrus, orbitofrontal cortex, and ventromedial cortex; temporal regions including the superior and medial temporal gyrus; other regions such as the fusiform gyrus, insula, anterior cingulate, among other structures [8-11].
Component 15 from the SBM analysis showed differences in the brains of schizophrenic and healthy volunteers in the middle frontal gyrus, precentral gyrus, subgyrus, postcentral gyrus, superior frontal gyrus, medial frontal gyrus, cingulate gyrus, and superior temporal gyrus.
A recent Spanish functional magnetic resonance brain imaging study demonstrated that schizoaffective disorder exhibits features that more closely resemble those of bipolar disorder than schizophrenia, including the finding that patients in clinical remission show failure of deactivation in the medial frontal gyrus, compared with healthy controls, Dr.
Increased activation was found in the bilateral dorsolateral prefrontal lobe, lateral ventral prefrontal cortex, medial frontal gyrus, insula, and right orbitofrontal gyrus.

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