megaloblastic anaemia


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megaloblastic anaemia

n
(Pathology) any anaemia, esp pernicious anaemia, characterized by the presence of megaloblasts in the blood or bone marrow
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.megaloblastic anaemia - anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrowmegaloblastic anaemia - anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemia
malignant anaemia, malignant anemia, pernicious anaemia, pernicious anemia - a chronic progressive anemia of older adults; thought to result from a lack of intrinsic factor (a substance secreted by the stomach that is responsible for the absorption of vitamin B12)
References in periodicals archive ?
The council's public health department also submitted a report highlighting the side effects of laughing gas including dizziness, nausea, megaloblastic anaemia and nerve damage.
It has been found that incidence of megaloblastic anaemia is increasing over last two decades.
Heavy metal poisoning, haemoglobinopathies, severe infections, sideroblastic anaemia, megaloblastic anaemia.
Iron deficiency, haemolytic and megaloblastic anaemia occur in diabetes through various mechanisms.
Megaloblastic anaemia: prevalence and causative factors.
megaloblastic anaemia (MA), myelodysplastic syndromes (MDSs), HIV
Folic acid: plasma levels usually indicate deficiency, and megaloblastic anaemia is frequently present in adults, but uncommon in children.
Megaloblastic anaemia. In: API Textbook of Medicine, 9th edn.
[12,14] Also, since the CHr is calculated from the reticulocyte MCV, patients with haemoglobinopathy associated with microcytosis will have a falsely low CHr, while patients with megaloblastic anaemia or macrocytic indices (MCV >100 fl), including some patients on antiretroviral therapy, will have a falsely elevated CHr.
Infantile vitamin [B.sub.12] deficiency was first reported in six South Indian infants, who presented at 7-12 months with megaloblastic anaemia, developmental regression and skin hyperpigmentation.
Megaloblastic anaemia due to vitamin B12 deficiency was diagnosed through a combination of clinical and laboratory findings, including clinical presentation, increased mean corpuscular volume (macrocytosis), hypersegmentation of neutrophils, and low vitamin B12 levels.