Seven cases of serious inflammatory brain disorders including encephalitis and meningoencephalitis
have been reported in Germany, while the other case has come from Spain.
The European Medicines Agency (EMA) has started an urgent review of the multiple sclerosis medicine Zinbryta (daclizumab) following 7 cases of serious inflammatory brain disorders in Germany, including encephalitis and meningoencephalitis
, and one case in Spain.
Naegleria fowleri causes primary amebic meningoencephalitis
(PAM); 0-8 laboratory-confirmed cases per year are documented in the United States) (1).
A brief historical sketch is given since the discovery of this amoeboflagellate in 1899 and the finding in 1970 that one species, Naegleria fowleri causes primary amoebic meningoencephalitis
(PAM) in man.
Murphy is terminally ill with granulomatous meningoencephalitis
, an inflammatory disease of the nervous system.
Herein we present a case of a 3-year-old boy with history of repeated diarrhoea and an episode of meningoencephalitis
The mortality rate of LM-related CNS infections has been reported to be 17%-62%, and LM cerebritis and cerebral abscess have a higher mortality rate than meningitis and meningoencephalitis
Epilepsy was diagnosed in (56%) followed by cerebral palsy (20%), post meningoencephalitis
sequalae (11%), intracranial hemorrhage (7%) and leukodystrophies (3%) as underlying cause of seizures.
On histologic examination, all 3 doves had moderate to severe meningoencephalitis
characterized by large numbers of plasma cells, lymphocytes, and macrophages with gliosis and astrocytosis.
The patient in South Carolina was confirmed on Tuesday to have been exposed to Naegleria fowleri (nuh-GLEER'-ee-uh FOW'-lur-ee), a one-celled organism that can cause primary amebic meningoencephalitis
, the Centers for Disease Control and Prevention reported.
An increasing number of cases of meningoencephalitis
related to herpesviruses has been reported in Latin America.
It discusses how the parasite causes primary amoebic meningoencephalitis
, clinical and laboratory diagnosis, chemotherapeutic and disinfection strategies, its pathogenesis, the host-damage response, its cell biology and speciation, cellular differentiation, its growth and life cycle, its ecology, and its relationship to other microbial organisms like viruses and bacteria.