mepacrine

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Related to mepacrine: Atabrine

mepacrine

(ˈmɛpəkrɪn)

(Pharmacology) Brit a drug, mepacrine dihydrochloride, one of the first synthetic substitutes for quinine, formerly widely used to treat malaria but now largely replaced by chloroquine. Formula: C23H30ClN3O.2HCl.2H2O. US name: quinacrine

[C20: from me(thyl) + pa(ludism + a)cr(id)ine]

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Noun

mepacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malaria

Atabrine, quinacrine, quinacrine hydrochloride

antimalarial, antimalarial drug - a medicinal drug used to prevent or treat malaria

anthelminthic, anthelmintic, helminthic, vermifuge - a medication capable of causing the evacuation of parasitic intestinal worms

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References in periodicals archive ?

Collins, "Binge ethanol-induced neurodegeneration in rat organotypic brain slice cultures: effects of PLA2 inhibitor mepacrine and docosahexaenoic acid (DHA)," Neurochemical Research, vol.

Chronic Alcohol Intoxication and Cortical Ischemia: Study of Their Comorbidity and the Protective Effects of Minocycline

Anti-protozoals: quinacrine, chloroquine and mepacrine.

Clinical profile of anaemia among HIV infected patients and its correlation with CD4+ count

Up to and including WWII troops based in mosquito-infested areas were given daily doses of Mepacrine to combat malaria.

Here and there

These drugs could be divided into two main types: acridines, which include mepacrine (quinacrine), used since 1930, and quinoleines, which include chloroquine (amodiaquine), proguanil, chlorproguanil, pyrimethamine, primaquine, quinocide, pamaquine.

Patriotic hygiene: tracing new places of knowledge production about malaria in Vietnam, 1919-75

Decreased ATP release is observed by lumi-aggregometry, and decreased mepacrine dense granule uptake is observed by flow cytometry.