mepacrine


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Related to mepacrine: Atabrine

mepacrine

(ˈmɛpəkrɪn)
n
(Pharmacology) Brit a drug, mepacrine dihydrochloride, one of the first synthetic substitutes for quinine, formerly widely used to treat malaria but now largely replaced by chloroquine. Formula: C23H30ClN3O.2HCl.2H2O. US name: quinacrine
[C20: from me(thyl) + pa(ludism + a)cr(id)ine]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mepacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malariamepacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malaria
Atabrine, quinacrine, quinacrine hydrochloride
antimalarial, antimalarial drug - a medicinal drug used to prevent or treat malaria
anthelminthic, anthelmintic, helminthic, vermifuge - a medication capable of causing the evacuation of parasitic intestinal worms
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References in periodicals archive ?
One patient had been sick for about 3.5 years prior to the mepacrine. Her top symptoms included burning of the peripheral nerves, itching, prickly arms, legs and torso and at its worst brain burning when she would eat ANY food (even low histamine).
Quinacrine for Complex Chronic Illnesses
Atabrine: A synthetic antibiotic developed by the German pharmaceutical company Bayer in 1931, Atabrine (the trade name for mepacrine, also called quinacrine) was the first manmade substitute for quinine, the anti-malarial drug of choice at that time.
WONDER DRUGS FOR VICTORY: America's arsenal of democracy gave the Allies not only death-dealing weapons of war, but also cutting-edge, lifesaving antibiotics
In the mast cell degranulation experiment, the order of [IC.sub.50] values of 17.6, 17.9, 22.3, 53.7, and 71.6 [micro]M was assignable to compounds 125, 97, positive control mepacrine, 77, and 20, respectively, against the release of [beta]-glucuronidase [18].
A Review on the Medicinal Plant Dalbergia odorifera Species: Phytochemistry and Biological Activity
Collins, "Binge ethanol-induced neurodegeneration in rat organotypic brain slice cultures: effects of PLA2 inhibitor mepacrine and docosahexaenoic acid (DHA)," Neurochemical Research, vol.
Chronic Alcohol Intoxication and Cortical Ischemia: Study of Their Comorbidity and the Protective Effects of Minocycline
Anti-protozoals: quinacrine, chloroquine and mepacrine.
Clinical profile of anaemia among HIV infected patients and its correlation with CD4+ count
* Up to and including WWII troops based in mosquito-infested areas were given daily doses of Mepacrine to combat malaria.
Here and there
These drugs could be divided into two main types: acridines, which include mepacrine (quinacrine), used since 1930, and quinoleines, which include chloroquine (amodiaquine), proguanil, chlorproguanil, pyrimethamine, primaquine, quinocide, pamaquine.
Patriotic hygiene: tracing new places of knowledge production about malaria in Vietnam, 1919-75
"I took mepacrine, which was voluntary at the time.
Bob's one of the last survivors from Burma's 'forgotten army' Pilot says: I'm no hero. We just tried to do a good job for our country

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