mepacrine


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Related to mepacrine: Atabrine

mepacrine

(ˈmɛpəkrɪn)
n
(Pharmacology) Brit a drug, mepacrine dihydrochloride, one of the first synthetic substitutes for quinine, formerly widely used to treat malaria but now largely replaced by chloroquine. Formula: C23H30ClN3O.2HCl.2H2O. US name: quinacrine
[C20: from me(thyl) + pa(ludism + a)cr(id)ine]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mepacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malariamepacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malaria
antimalarial, antimalarial drug - a medicinal drug used to prevent or treat malaria
anthelminthic, anthelmintic, helminthic, vermifuge - a medication capable of causing the evacuation of parasitic intestinal worms
References in periodicals archive ?
Collins, "Binge ethanol-induced neurodegeneration in rat organotypic brain slice cultures: effects of PLA2 inhibitor mepacrine and docosahexaenoic acid (DHA)," Neurochemical Research, vol.
Up to and including WWII troops based in mosquito-infested areas were given daily doses of Mepacrine to combat malaria.
These drugs could be divided into two main types: acridines, which include mepacrine (quinacrine), used since 1930, and quinoleines, which include chloroquine (amodiaquine), proguanil, chlorproguanil, pyrimethamine, primaquine, quinocide, pamaquine.
Decreased ATP release is observed by lumi-aggregometry, and decreased mepacrine dense granule uptake is observed by flow cytometry.