mephobarbital

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Related to mephobarbital: phenobarbital, secobarbital

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Noun

mephobarbital - a long-acting crystalline barbiturate (trade name Mebaral) used as a sedative and as an anticonvulsant in the treatment of epilepsy

Mebaral

anticonvulsant, anticonvulsant drug, antiepileptic, antiepileptic drug - a drug used to treat or prevent convulsions (as in epilepsy)

barbiturate - organic compound having powerful soporific effect; overdose can be fatal

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References in periodicals archive ?

CYP2C19*16 was reported in a Japanese subject demonstrating a lowered capacity to hydroxylate mephobarbital (9).

Genetic polymorphism of CYP2C19 & therapeutic response to proton pump inhibitors

Some antiepileptic drugs--carbamazepine, oxcarbazepine, phenytoin, barbiturates (phenobarbital, mephobarbital and primidone), and topiramate--enhance the cytochrome P-450 enzyme system.

Epileptic women need reliable contraceptives

Classification and Pharmacologic Management of Seizures Seizure First Line Agents New/Alternative Agents Simple Partial phenytoin primidone carbamazepine phenobarbital valproic acid gabapentin lamotrigine felbamate topiramate ethotoin mephenytoin Complex partial phenytoin primidone carbamazepine valproic acid phenobarbital mephobarbital gabapentin lamotrigine felbamate topiramate amobarbital Absence clonazepam methsuximide ethosuximide phensuximide valproic acid lamotrigine trimethadione Myoclonic valproic acid clonazepam Tonic Clonic phenytoin/fosphenytoin phenobarbital carbamazepine primidone valproic acid topiramate Stares epilepticus phenytoin/fosphenytoin diazepam lorazepam phenobarbital diazepam secobarbital pentobarbital