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The trial will assess the safety and efficacy of cefepime/VNRX-5133 as compared with that of meropenem using clinical cure and microbiological eradication as the primary composite efficacy endpoint.
M2 PRESSWIRE-August 9, 2019-: How Meropenem Market will Shape having Biggies with Strong Fundamentals
Tenders are invited for tender for the supply of meropenem 1g iv injections - ct2118/2019
This expanded use is based on results of the company's pivotal Phase 3 ASPECT-NP trial that compared ZERBAXA 3g (ceftolozane 2g and tazobactam 1g) intravenously every eight hours to meropenem (1g intravenously every 8 hours) for eight to 14 days for the treatment of 726 adult patients with HABP/VABP.
The results demonstrated non-inferiority of an investigational dose of ZERBAXA to meropenem, the active comparator, in the primary and key secondary endpoints.
Susceptibility to imipenem and meropenem was tested by disk difusion and broth microdilution test, and interpreted according to the CLSI criteria (21-23).
The suggested indicator carbapenem is meropenem since it offers the best balance of sensitivity and specificity for the detection of CPE.
Linezolid, Vancomycin, Amoxycillin, Cefoperazone and Meropenem are the most effective antibiotics for treating post-surgical wound infections.
MexAB-OprM is an efflux system belonging to the Resistance-Nodulation-Division (RND) family, which has the broadest substrate profile of [beta]-lactams including meropenem; therefore, an expression level increase has been extensively related to carbapenem resistance (9,10).
Lezyonu hizla progrese olan hastaya ampirik olarak meropenem 3x1 gr ve vankomisin 2x1 gr IV baslandi.
Based on antimicrobial susceptibility testing (Table 1)by the VITEK[R]2 system (bioMerieux, Marcy-l'Etoile, France), the antibiotic regimen was switched to amikacin (250 mg 12/12 h) and meropenem (1 g 8/8 h).
In this trial, the CAZ-AVI combination was augmented with metronidazole, and compared to meropenem, in 72-hour infusions.
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- Meromorphic Conformal Field Theory
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- Meromorphic function
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- Meropenem Yearly Susceptibility Test Information Collection
- Merosin heavy chain
- Merosin-Deficient Congenital Muscular Dystrophy