metabotropic receptor


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Related to metabotropic receptor: Metabotropic glutamate receptor

metabotropic receptor

(mɪˌtæbəˈtrɒpɪk)
n
(Physiology) physiol an indirect receptor which initiates an intracellular biochemical cascade after it is triggered by an agonistic ligand. Compare ionotropic receptor
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References in periodicals archive ?
Glutamate can also bind to a metabotropic receptor.
1] is a G-protein-coupled metabotropic receptor that increases activity of the enzymes adenylyl cyclase and phospholipase C.
Two classes of glutamate receptors exist: ionotropic receptors (iGluRs), and metabotropic receptors (mGluRs).
The modulation of glutamatergic ionotropic or metabotropic receptors is shown in Table 4.
Metabotropic receptors generally produce slower and longer-lasting reactions at the synapse that have modulatory effects rather than generate new nerve signals.
So-called metabotropic receptors , responding to the same neurotransmitters, set off chemical cascades in the receiving nerve cells, so-called "second messenger" systems, chains of chemical processes activating synthesis of neurotransmitters, of receptors and of modulators, changing the reactivity of the nerve cell and of the system it subserves.