Also found in: Medical, Encyclopedia, Wikipedia.


1. Normal transformation of tissue from one type to another, as in the ossification of cartilage to form bone.
2. Transformation of cells from a normal to an abnormal state.

met′a·plas′tic (-plăs′tĭk) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Physiology) the transformation of one kind of tissue into a different kind
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌmɛt əˈpleɪ ʒə, -ʒi ə)

the transformation of one type of cellular tissue into another.
met`a•plas′tic (-ˈplæs tɪk) adj.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
Mentioned in ?
References in periodicals archive ?
Conclusion: Permanent impairment in the conjugation of cell and tissue components in mucosa accompanied by the change of an epithelial layer synthetic function with the impaired physicochemical properties of gastric mucin results in intestinal metaplasia as early as in childhood.
Of the Hp-positive patients, 331(82.5%) had chronic active gastritis, 56(13.9%) had chronic non-specific gastritis, 11(2.7%) had gastritis with intestinal metaplasia and 4(0.9%) had chronic atrophic gastritis (Table-2).
Gastric foveolar metaplasia was also identified (Figure 4(a), blue square, and Figure 4(c)).
Chronic inflammation was seen in 70 cases (70%), activity in 15 cases (15%), glandular atrophy in 2 cases (2%) and intestinal metaplasia in 2 cases (2%).
Apocrine carcinomas also known as apocrine metaplasia or sweat gland carcinoma are very rare variant of invasive breast malignancies with an incidence less than 1%.
Sergii Vernygorodskyi from the Department of Pathological Anatomy at Vinnitsa National Pirogov Memorial Medical University, Ukraine, has studied the role of the infamous corkscrew-shaped "gut bug" in the formation of intestinal metaplasia of the gastric mucosa (mucous membrane layer of the stomach).
CIN starts at the transformation zone, especially in relation to the squamous metaplasia and reserve cell hyperplasia.
Microscopic examination revealed that the mass was a benign polyp with osseous metaplasia. Many mature lamellar bony trabeculae were present within it.
Group A and Group B had significant high intestine metaplasia and mucosal inflammation score than those in control group.
GlobalData's clinical trial report, "Myeloid Metaplasia Global Clinical Trials Review, H2, 2015" provides an overview of Myeloid Metaplasia clinical trials scenario.
We hypothesized that Hyal and HAS expressions also change in bronchial metaplasia and dysplasia, and in atypical adenomatous hyperplasia, which are thought to be stages in the development of squamous cell lung carcinoma (25,26) and adenocarcinoma, respectively.
To increase the accuracy of endoscopic diagnosis, we carried out an additional chromoendoscopy with methylene blue staining allowing the detection of foci of intestinal metaplasia (IM) of gastric mucosa which were unrecognized by routine endoscopy.