methylation


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Related to methylation: acetylation

meth·yl·a·tion

 (mĕth′ə-lā′shən)
n.
1. An alkylation process involving addition of, or substitution by, a methyl group.
2. The process of treating something with methyl alcohol.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
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References in periodicals archive ?
Down-regulation of promoter methylation level of CD4 gene after MDV infection in MD-susceptible chicken line.
Understanding the nutritional biochemistry in methylation can aid treatment plans by creating a protocol more likely to benefit the patient.
In recent years, a growing body of evidence suggested that the state of DNA methylation, an epigenetic modification that plays crucial roles in gene regulation and genomic stability (Jones 2012), was closely related to age over long time periods (Christensen et al.
Epigenetic regulation such as DNA methylation is a regulatory process that depends on stochastic and environmental stimuli; it is a process usually associated with gene repression that, in mammals, occurs mainly at cytosine residues located within CpG islands (9).
DNA methylation is a well-established and extensively studied epigenetic phenomenon [1-4].
According to the researchers at the University of North Carolina, the reason for this effect could be explained by DNA methylation of genes in breast cancer tumours or peripheral blood.
For CRC development, DNA methylation is accepted as third underlying mechanism after CIN and MSI.
We recently suggested that epigenetic modifications, such as DNA methylation, might explain discrepant association signals sometimes obtained in studies on human patellar tendinopathy (El Khoury et al., 2018).
Several factors can play a part in the development of CHD such as genetic susceptibility, epigenetic mechanism and environmental effects.1 Among these factors DNA methylation is much known to be associated with CHD, that take place during pregnancy.
The purpose of this study was to conduct a genome-wide screening of aberrant methylation loci in partial lesion tissues of patients with nonsyndromic CL (NSCL) and preliminarily validate candidate dysmethylated genes associated with NSCL.