methysergide


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methysergide

(ˌmɛθɪˈsɜːdʒaɪd)
n
(Pharmacology) a drug, C21H27N3O2, used in the form of its maleate to prevent migraines
References in periodicals archive ?
Effects of U46619 on contractions to 5-HT, sumatriptan and methysergide in canine coronary artery and saphenous vein in vitro.
Three other agents are not available in the United States: flunarizine (an agent with calcium channel-blocking activity) and two serotonin antagonists, pizotifen and methysergide (a semisynthetic ergot alkaloid).
While diffuse pleural thickening is commonly associated with exposure to commercial forms of asbestos, it can also be caused by collagen vascular diseases (systemic lupus erythematosus, rheumatoid arthritis), drugs (methysergide and chemotherapy), infection (TB or chronic fungal), and sarcoidosis and can also be idiopathic in nature.
Ghi, "Combined action of thioperamide plus scopolamine, diphenhydramine, or methysergide on memory in mice," Pharmacology Biochemistry and Behavior, vol.
La FPR secondaire peut etre le resultat d'un anevrisme de l'aorte, d'une radiotherapie anterieure, d'une chirurgie abdominale, de traumatismes, de tumeurs retroperitoneales primaires ou metastatiques, d'infections (tuberculose, histoplasmose, actinomycose) et de la prise de medicaments (ergotamine, methyldopa, beta-bloquants, methysergide, bromocriptine, hydralazine) (tableau 1).
Other proposed treatments include beta blockers, anticonvulsants, methysergide, amantadine, aripiprazole, and haloperidol.
(1) Amyloidosis (AL, ATTR, SSA) (2) Sarcoidosis (3) Hemochromatosis (4) Eosinophilic myocardial disease (5) Idiopathic RCM (6) Progressive systemic sclerosis (scleroderma) (7) Postradiation therapy (Hodgkin's lymphoma, breast cancer etc) (8) Anderson Fabry disease (9) Danon's disease (10) Friedreich's ataxia (11) Diabetic cardiomyopathy (restrictive phenotype) (12) Drug induced (anthracycline toxicity, methysergide, ergotamine, mercurial agents, etc.) (13) Mucopolysaccharidoses (Hurler's cardiomyopathy) (14) Myocardial oxalosis (15) Wegener's granulomatosis (16) Metastatic malignancies Table 2: Differential diagnosis between restrictive cardiomyopathy and constrictive pericarditis.
SOME DRUGS THAT CAN CAUSE OR EXACERBATE HEART FAILURE Condition Drugs Arrhythmia dronedarone, flecainide, disopyramide, sotalol Cancer anthracydines and many other agents Depression citalopram, lithium Diabetes thiazolidinediones, dipeptidyl peptidase-4 inhibitors Fungal infections amphotericin B Hypertension doxazosin, diltiazem, verapamil, moxonidine Malaria chloroquine, hydroxychloroquine Migraines ergotamine, methysergide Pain prescription and nonprescription NSAIDs Parkinson's pergolide, pramipexole, bromocriptine Platelet disorders anagrelide, cilostazol Pulmonary disease bosentan, epoprostenol, albuterol Rheumatologic TNF-a inhibitors diseases
There are isolated reports of ischemic colitis associated with other drugs, like NSAIDs: alosetron (Lotronex, GlaxoSmithKline, Philadelphia, Pennsylvania), used for the management of severe diarrhea in irritable bowel syndrome in women only; pseudoephedrine; interferon; dopamine; and methysergide.
Animals were pre-treated by oral administration of crude extract (50,100 or 150 mg/kg), F1 or F2 (1,10, or 50 mg/kg), promethazine (30 mg/kg), or methysergide (5 mg/kg).
An older clinical trial found that supplementation with 2 to 4 g of L-tryptophan daily was as effective at preventing migraine attacks as the ergot medication methysergide (Sicuteri 1973).
CP-55,940, Naloxone, U-69,593, muscimol, MK801, yohimbine and methysergide were obtained from Tocris Cookson Ltd.