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Related to metoclopramide: metoclopramide HCl


A dopamine antagonist, C14H22ClN3O2, that stimulates movement in the upper gastrointestinal tract, used in its hydrochloride form to treat nausea, gastroesophageal reflux, and diabetic gastroparesis.

[French métoclopramide : mét(h)-, meth- + o(xy)-, oxy- + c(h)lo(ro)-, chloro- + pr(ocaïn)amide, procainamide, a drug used to treat arrhythmia (procaïne, procaine + amide, amide).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


n metoclopramida
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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Metoclopramide. One systematic review that looked at the efficacy of metoclopramide for gastroparesis identified one small RCT and 3 smaller placebo-controlled crossover trials.
However, IV dexketoprofen seems to be faster and more effective than metoclopramide and ibuprofen.
In addition, Manaa and Seif found that the combination of Dexamethasone with Metoclopramide was not significantly more effective than single administration of Dexamethasone in the prophylaxis of PONV in patients undergoing maxillofacial surgery.
The factors that increased the risk of a long hospital stay included patients with an ASA class 3, a history of previous acute cholecystitis, cholangitis, or pancreatitis, a history of cirrhosis, being on long-term anticoagulation with warfarin, having standard-pressure pneumoperitoneum (14mmHg), having been given metoclopramide as an intraoperative antiemetic drug, having an intraoperative cholangiogram, having an operative time of more than 60 minutes, having an incidental perforation of the gallbladder, using an abdominal drain, PONV, an NRS pain score more than 3, a parenteral analgesia requirement of more than 2 doses, an oral analgesia requirement of more than 2 doses, complications, and private ward admission.
In this prospective, case-control study, we evaluated the efficacy of combined electroacupuncture/metoclopramide treatment with that of metoclopramide only in improving gastric emptying in critically ill neurosurgical patients.
Material and Methods: Dose response curve of ranitidine and metoclopramide were constructed by adding cumulatively increasing concentrations of the two drugs on isolated duodenum of rabbits separately.
In conjunction, a request for proprietary name review for Gimoti will be included if and when the company submits a New Drug Application (NDA) for EVK-001 (metoclopramide nasal spray).
Key clinical point: Intravenous metoclopramide and diphenhydramine relieved headaches more effectively than did codeine in pregnant patients who presented urgently.
In adult rats, the rate of gastric emptying is modulated by properties of the diet, including its caloric content and osmotic properties.[11] Delayed gastric emptying has been documented in severe head injuries and in such cases metoclopramide has no significant prokinetic effect on gastric emptying.[11]
The Question: Do metoclopramide and domperidone increase breast milk production?
Malbora (1) and his colleagues reported metoclopramide in addition to corticosteroid in the treatment of a patient with steroid refractory Diamond-Blackfan (D-B) anemia in the recent issue of the Journal (1).