microglia


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Related to microglia: Astrocytes, Oligodendrocytes

mi·cro·gli·a

 (mī′krō-glē′ə, -glī′-)
pl.n.
Small neuroglial cells of the central nervous system that have long processes and act as phagocytes at sites of neural damage or inflammation, destroying pathogens and damaged cells.

mi′cro·gli′al adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

microglia

(ˌmaɪkrəʊˈɡlɪə)
n
(Anatomy) one of the two types of non-nervous tissue (glia) found in the central nervous system, having macrophage activity. Compare macroglia
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.microglia - neuroglial tissue of mesodermal origin that can become phagocyticmicroglia - neuroglial tissue of mesodermal origin that can become phagocytic
glia, neuroglia - sustentacular tissue that surrounds and supports neurons in the central nervous system; glial and neural cells together compose the tissue of the central nervous system
microgliacyte - a cell of the microglia that may become phagocytic and collect waste products of nerve tissue
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
In active microglia, Gal3 accumulates, disabling cells from clearing damaged materials and even triggering more severe inflammation, Siew said.
In the late teenage years, a normal extensive pruning of the number of connections between nerve cells, so-called synapses, and takes place through microglia (the brain's immune cells) selectively degrading less desirable connections.
They suggest that reinforcing the activity of such immune cells -- known as microglia -- could slow or stop the proliferation of tau tangles, and potentially delay or prevent Alzheimer's dementia.
Microglia increase inflammatory responses in iPSC-dervied human BrainSpheres.
In a separate oral presentation in the Best Pediatric Abstracts Session, Kevin Goncalves, Ph.D., Magenta Therapeutics, highlighted data demonstrating that the high stem cell doses in MGTA-456 accelerate and improve engraftment of human microglia in the brains of transplanted mice.
(FCDI) announced the launch of iPSC-derived iCell Microglia, immune cells of the central nervous system responsible for fundamental physiological and pathological processes.
The molecule works by cooling the "brains on fire", turning down inflammatory activity caused by immune cells in the brain called microglia, and allowing neurons to function normally, according to the study published in the journal Science Translational Medicine.
Microglia are derived from mesodermal cells belonging to the hematopoietic lineage and are the macrophage-like cells of the central nervous system (CNS) that are distinguished from other glial cells, such as astrocytes and oligodendrocytes (6).
The glial cells, or microglia, release cytokines, which are substances that activate more microglia to help eliminate the cause of the inflammation.
(FCDI) has entered into an exclusive patent license agreement with the University of California - Irvine (UCI) to license and commercialize UCI's technologies for derivation of microglia in the commercial research field and also a nonexclusive patent license agreement to commercialize microglia media formulation.
This could affect their brain's immune system cells (microglia) and drive inflammation that could impair memory functions, much like Alzheimer's, and destroy information-bearing synapses or connections between brain cells.