The experiment results revealed that IC50 values tested with the whole compounds for GST, [alpha]-amylase and [alpha]-glycosidase enzymes were found to be
micromolar level, but IC50 values tested with the whole compounds for AChE and BChE enzymes were detected to be nanomolar levels.
Our results suggest that lower
micromolar doses of [beta]2-agonist can be used to elicit skeletal muscle growth and development with minimum potential for necrosis or apoptosis.
This effect did not occur if their mothers had choline levels greater than 7
micromolar during gestation.
Best studied is oxybenzone, for which human plasma concentrations (free form) in the very low
micromolar range were found after topical application of oxybenzone containing sunscreen in a study with a very limited number of participants (n = 3).
Belinostat (Beleodaq or PXD101) is a novel hydroxamatetype HDAC inhibitor that exhibits in vitro cytotoxicity at low
micromolar concentrations and it is active for the treatment of ovarian cancer, CTCL, thymoma or thymic carcinoma, and myelodysplastic syndrome.
This analogue approach resulted in four more hits of
micromolar activity against LsrK.
Further investigation would greatly reduce the concentration of GnCl for these peptides to analyze stability in a
micromolar regime.
[9] In this study, oral curcumin gavage was planned at a dose of 200 mg/kg for 1 week to allow for curcumin to the diffuse and accumulate in the cells at
micromolar levels contained in the serum.
In this colorimetric method, the presence of antioxidants causes a loss of color in dark-blue-green-colored ABTS, with the color change recorded at 660 nm and the results given in
micromolar trolox liters.
Significant effects were found with very low (
micromolar) concentrations of EIP and [H.sub.2][O.sub.2].