microtubule


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Related to microtubule: Intermediate filaments

mi·cro·tu·bule

 (mī′krō-to͞o′byo͞ol, -tyo͞o-)
n.
Any of the cylindrical hollow tubulin-containing structures that are found in the cytoplasm, cilia, and flagella of eukaryotic cells and are involved in determining cell shape and structure and directing the movement of organelles and chromosomes. Microtubules, along with microfilaments and intermediate filaments, make up a cell's cytoskeleton.

mi′cro·tu′bu·lar adj.

microtubule

(ˌmaɪkrəʊˈtjuːbjuːl)
n
(Biology) biology a tubular aggregate of protein subunits that forms structures, such as the mitotic spindle or the cilia of animal cells or of protozoans, in which the protein interacts with other proteins to generate various cellular movements

mi•cro•tu•bule

(ˌmaɪ kroʊˈtu byul, -ˈtyu-)
n.
an ultrafine cylindrical structure in the cell cytoplasm, involved in shape and transport.
[1960–65]

mi·cro·tu·bule

(mī′krō-to͞o′byo͞ol)
Any of the tube-shaped structures that help cells maintain their shape and assist in forming the cell spindle during cell division. Microtubules are found in the cytoplasm of the cells of all organisms except bacteria.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.microtubule - a microscopically small tubule
tubule - a small tube
References in periodicals archive ?
Composed of heterodimers that comprise of two tubulin isoforms, microtubules play dynamic role in chromosomal movement during mitosis, intracellular transportation, organelle motion and organization, featured by intrinsic instability, for instance, the haploid microtubules.
They found that, in ground squirrel neurons, the microtubule cytoskeleton remains intact while it deteriorates in the neurons of humans and other nonhibernating animals, including rats.
The researchers were able to show that Akna recruits and anchors microtubules at the centrosome.
(1) The structure of the ciliary apparatus consists of a microtubule-base-daxoneme, which is a highly ordered structure made up of nine peripheral microtubule doublets that are arranged around a central core.
The first possibility is physical force from astral microtubules. At anaphase, because of the force created at astral microtubule disassembly by the cortical motor protein, dynein, the astral spindle was pulled toward the cortex.
Therefore, we implemented 0.5mg a low-dose adjuvant colchicine once daily with a view to preventing scar ventricular tachycardia (VT) of the patient in addition to conventional medication to ensure the microtubule destabilization and the pharmacological scar dechanneling.
Studies have reported that MAP4 plays an important role in microtubule assembly and stabilization [8, 11, 12].
Both tau protein hyperphosphorylation and aggregation impair microtubule formation, and alter neuronal dynamics and stability.
Takahashi et al., "A direct test of the hypothesis that increased microtubule network density contributes to contractile dysfunction of the hypertrophied heart," American Journal of Physiology-Heart and Circulatory Physiology, vol.
On the basis of our observations of the changes of Cx43 after ischemia, we analyzed its mechanism from the aspects of microtubule transport and endocytosis for an in-depth understanding of the factors that influence Cx43 functional changes and provide a theoretical basis for selecting a method of clinical intervention.
Therefore, the mechanism of UV-B radiation-enhanced chromosomal aberrations probably involves injury to microtubule arrays (Gao et al., 2010; Guo et al., 2010).

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