Bloodstream dissemination leads to
miliary tuberculosis with lesions in many organs and a high mortality rate.
The rates for causes avoidable by vaccine-preventable actions (
miliary tuberculosis, acute hepatitis B and tetanus) are low.
Such an imaging feature is also associated with the more common conditions of
miliary tuberculosis or other type of infectious pneumonia, resulting in high risk of misdiagnosis.
Isolation of MTBC from blood cultures has been reported since the early 20th century from patients with
miliary tuberculosis. (2) However, blood culture in mycobacterial infections was rarely requested before the HIV era, (3) but its use has been boosted by improvements in blood culturemedia, mainly for differential diagnosis with Mycobacterium avium-intracellulare complex or Histoplasma capsulatum.
Endogenous infection is secondary to a preexisting primary focus and may result from contiguous (orificial tuberculosis, scrofuloderma), hematogenous (acute
miliary tuberculosis, tuberculous gumma, and lupus vulgaris), or lymphatic dissemination (lupus vulgaris) [2,16].
Miliary histoplasmosis is a rare clinical manifestation that may mimic
miliary tuberculosis and diagnosis may be delayed if a broad differential is not considered in patients undergoing workup for miliary pulmonary nodules.
Phenotypic and genotypic diagnosis of bone and
miliary tuberculosis in an HIV positive patient in Bogota, Colombia.
Patients aged less than 18 years, patients with extrapulmonary or
miliary tuberculosis, and patients with any compelling conditions were excluded from this study.
In the article titled "
Miliary Tuberculosis Presenting with ARDS and Shock: A Case Report and Challenges in Current Management and Diagnosis" [1], the name of the fifth author was given incorrectly as Neil Bhagwandass.
CNS tuberculosis can manifest in a variety of forms, including tuberculous meningitis, tuberculomas, tuberculous abscesses, tuberculous cerebritis, and
miliary tuberculosis. Among these, tuberculous meningitis is the most common manifestation of CNS involvement across all age groups [7].
A 28-year-old male patient, recently diagnosed with HIV infection and
miliary tuberculosis (TB) based on characteristic chest CT findings and positive sputum culture, presented to the emergency department with new onset of ataxia (Figure 1A).
We believe that
miliary tuberculosis resulting in adrenal insufficiency (or Addison's disease) may have resulted in the oral and physical symptoms witnessed by the Inuit.