Circulation among Wild and Domestic Mammals, Amazon Region, Brazil
Objective: The long-term goal of this proposal is to understand the molecular mechanisms of the replication cycle ofnucleocytoplasmic large DNA viruses that attracted attention after the discovery of the giant Mimivirus
Viruses infecting eukaryotic hosts remain less well characterized, although recent metagenomic efforts have begun to elucidate the distribution of nucleo-cytoplasmic large DNA viruses (NCLDVs) and Mimivirus
gene homologs in pelagic samples as part of the Tara Oceans project (Hingamp et al.
, the microbe was so large that researchers could see it with a light microscope.
Son yillarda bu listeye once enterovirus, PIV tip 4, mimivirus
, daha sonra sirasiyla 2001 yilinda "insan metapnomovirus" (hMPV), 2003 yilinda koronavirusler (SARS'dan sorumlu CoV, HCoV NL63 ve HKUT), 2005' de "human Bocavirus" (HBoV), parvovirus tip 4 ve 5, nihayet 2007'de de human polyomavirus KI (KIV) ve WU (WUV) gibi yeni etkenlerin eklendigi gorulmektedir (2).
It just beats the previous record holder, Mimivirus
, which was found in a water cooling tower in the UK in 1992.
Like the Mimivirus
, previously thought to be the largest, it survives in freshwater amoebae.
The only differences to date between the Mimivirus
and small obligate intracellular bacteria are the absence from the virus of ribosomal proteins and of proteins involved in energy metabolism, and multiplication of the virus by assembly of pre-formed subunits.
Ejemplos de ello son el virus de la hepatitis C (VHC), el metaneumovirus humano (MNVH) y el mimivirus
An international group of specialists in infectious diseases discuss newly recognized diseases, previously known pathogens that present new challenges, and domestic and international threats, including the 2009 flu pandemic in Australia, the reemergence of human adenovirus 14, acanthanmoeba polyphaga mimivirus
, the global impact of hepatitis E, human T-lymphotropic virus 1 in indigenous populations in Australia, cytomegalovirus infection in transplant recipients, HIV-associated malignancies, the global spread of multidrug-resistant gram-negative bacilli, sepsis in sub-Saharan Africa, neglected tropical diseases, infections in long-term care facilities and mobile populations, infectious plant diseases, and the One World-One Health initiative.
1/2 micrometro es el diametro del <<gigantesco>> Mimivirus
, descubierto en 1992.
Ejemplo de ello es el avance tecnologico, lo cual ha hecho posible la identificacion de agentes infecciosos como el virus de la hepatitis C, que resulto ser el principal agente etiologico de las hepatitis no causadas por los virus de hepatitis A y B (1), Los metodos de biologia molecular y la modificacion de medios y tecnicas de cultivo han propiciado el descubrimiento de dos nuevos virus causantes de infecciones respiratorias, el mimivirus
y el metaneumovirus (2, 3).