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Noun1.mithramycin - an antineoplastic drug (trade name Mithracin) used to treat cancer of the testes
antineoplastic antibiotic - an antibiotic drug used as an antineoplastic in chemotherapy
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References in periodicals archive ?
DAPI, DIPI, Hoechst 33258, and Hoechst 33342 bind to AT-rich regions whereas chromomycin A mithramycin, and olivomycin bind to GC-rich regions.
The study highlighted the decrease of MCL-1 expression in cancer lines after treatment with sorafenib and mithramycin A, along with a decrease in cell replication, suggesting that the decline of MCL-1 expression could influence the process of malignant transformation [67].
Maibach, "Mithramycin as a possible cause of toxic epidermal necrolysis (Lyell's syndrome)," California Medicine, vol.
Cur, Mithramycin (MTM), and 2,3,5-triphenyltetrazolium chloride (TTC) were purchased from Sigma (St.
Zhang et al., "Mithramycin represses basal and cigarette smoke-induced expression of ABCG2 and inhibits stem cell signaling in lung and esophageal cancer cells," Cancer Research, vol.
The cytotoxicity data are shown in supplementary Table 5, and the clinically applied anticancer agent mithramycin was used as reference compound (Chen et al.
There are studies showing that K562 cells treated with DNA-binding agents, such as mithramycin, have led to erythroid differentiation and sharp enhancement of [gamma]-globin mRNA level [50].