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Tolerance or immunity to a poison acquired by taking gradually larger doses of it.

[After Mithridates VIwho is said to have acquired tolerance for poison.]

mith′ri·dat′ic (-dăt′ĭk) adj.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Medicine) immunity to large doses of poison by prior ingestion of gradually increased doses
mithridatic adj
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


the production of immunity against the action of a poison by consuming it regularly in gradually larger doses.
See also: Poison
-Ologies & -Isms. Copyright 2008 The Gale Group, Inc. All rights reserved.
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These changes, according to the concept of Mithridatism contribute to maintaining longevity.