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Tolerance or immunity to a poison acquired by taking gradually larger doses of it.
[After Mithridates VIwho is said to have acquired tolerance for poison.]
mith′ri·dat′ic (-dăt′ĭk) adj.
(Medicine) immunity to large doses of poison by prior ingestion of gradually increased doses
the production of immunity against the action of a poison by consuming it regularly in gradually larger doses.See also: Poison