mitogen


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Related to mitogen: Pokeweed mitogen

mi·to·gen

 (mī′tə-jən)
n.
An agent that induces mitosis.


mi′to·gen′ic (mī′tə-jĕn′ĭk, mĭt′ə-) adj.
mi′to·ge·nic′i·ty (-jə-nĭs′ĭ-tē) n.

mitogen

(ˈmaɪtədʒən)
n
(Biology) any agent that induces mitosis
mitogenic, mitogenetic adj

mi•to•gen

(ˈmaɪ tə dʒən, -ˌdʒɛn)

n.
any substance or agent that stimulates mitosis.
[1950–55; mito (sis) + -gen]
mi`to•gen′ic (-ˈdʒɛn ɪk) adj.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mitogen - an agent that triggers mitosismitogen - an agent that triggers mitosis  
agent - a substance that exerts some force or effect
Translations

mi·to·gen

n. mitógeno, sustancia que induce mitosis celular.
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References in periodicals archive ?
The mitogen activated protein kinase signal transduction pathway: from the cell surface to the nucleus.
18 January 2012 - German Wilex AG (ETR:WL6) said on Wednesday it had successfully completed a Phase I dose escalation trial with its oral Mitogen activated protein kinase (MEK) inhibitor WX-554 demonstrating activity, safety and tolerance in healthy volunteers.
(Fabaceae) on mitogen response of the spleen cells in Graffi tumor bearing (GTBH) and healthy hamsters were reported.
The mitogen phytohemagglutinin is used as an assay control and saline as a negative control or "nil antigen." After incubation, the plasma is separated and the concentration of interferon-[gamma] measured by enzyme-linked immunosorbent assay.
In this group, social QoL was also negatively associated with %HLA-DR+ in T cells (r = -.245) and mitogen stimulated T cell function (IL2R expression on T cells after 72 h incubation with PHA; r = -.243).
In addition to pregabalin, other promising investigational approaches include nerve growth factor blockade as well as the targeting of proinflammatory glial cells and cytokines such as p38 mitogen activated protein (MAP) kinase.
The cells were incubated for 96h with both VA-E at 0, 10, 100 and 1000 [micro]g/ml, interleukin-6 at 1000 U/ml, and pokeweed mitogen and phytohaemagglutinine at 2.5 [micro]g/ml.
The murine splenocytes were used to assess lymphocyte proliferation response after mitogen stimulating for 20h.
The mitogen phytohemagglutinin is used as an assay control and saline as a negative control or "nil antigen." After incubation, the plasma is separated and the interferon-[gamma] level measured by enzyme-linked immunosorbent assay The QFT score is based on the proportion of interferon-[gamma] released in response to tuberculin, compared with phytohemagglutinin.
The results obtained show that most of the extracts exerted inhibitory effect on tumor as well as on mitogen activated normal spleen cell growth.
Such effects were mediated by local conversion of DHEA to estrogen, acting through the estrogen receptor, and vitro studies suggest a direct effect on specific pro-inflammatory cytokine production by macrophages via mitogen activated kinase (MAP) and phosphatidylinositol 3 (PI3) kinase pathways.

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