In contrast, an increase in the RNA/DNA ratio would indicate an increase in RNA synthesis without a change in the amount of DNA (i.e., number of nuclei) in the tissue and would suggest that no mitotic activity
The results also indicate FSH increases mitotic activity
and finally EGF and FSH in combination worked to up-regulate cell proliferation.
We still noticed the presence of the cytotrophoblast: cells with relatively large nuclei, vesiculated, clear cytoplasm, with mitotic activity
, being observed polyploidy in some of them (Fig.
"Since the risk of mitotic errors is proportional to cellular mitotic activity
, X monosomy may be secondary to increased mitotic activity
after exposure to chemical and physical genotoxins, which are known to cause chromosomal loss in blood cells, or to an inherited genetic trait," the researchers said.
This not only renders mammographic screening more effective in these high-risk women, it also lessens their breast cancer risk, since the reduction in mammographic densities reflects decreased mitotic activity
of breast epithelial cells, Dr.
To elucidate when DNA endoreduplication is most vulnerable to high temperature, both the 4- and 6-d HTTs were imposed at the time of high mitotic activity
(4 to 10 DAP) and when DNA endoreduplication had been initiated (10 DAP).
There is high mitotic activity
including atypical mitoses (Figure 2(c)).
Despite the classical form, many cytological features such as high mitotic activity
and increased cellularity associated with aggressive behavior were described in the literature (4).
, hemorrhage, and subepidermal blistering could be seen.
Aggressive-growth BCC variants, including micronodular, infiltrative, morpheaform, and metatypical, share features of increased cell necrosis, mitotic activity
, and stromal proliferation, with a decreased demonstration of stromal retraction, deeper growth, and less circumscription.
The rate of nuclear atypia, presence of tumor necrosis, and high mitotic activity
[mitosis if it is [greater than or equal to]10/high-power field (HPF)] are important criteria for defining malignancy.
In PEComas, presence of high mitotic activity
[>1/50 high-power field (hpf)], atypical mitotic figures, coagulative tumor necrosis, pleomorphism and nuclear atypia, hypercellularity, infiltrative growth pattern, and big tumor size (>70 mm) have been shown to be associated with the malignancy potential (17).