molecular chaperone


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Related to molecular chaperone: Chaperone molecule

molecular chaperone

n.
References in periodicals archive ?
Binding immunoglobulin protein (BiP), also known as 78 kDa glucose-regulated protein (GRP78), is a lumen-resident molecular chaperone which is markedly up-regulated under ER-stress, dissociating from the three sensor proteins to activate each UPR pathway when unfolded and misfolded proteins are accumulated in the ER.
Heat shock protein-72 (HSP-72) is a molecular chaperone that protects against IR; AAPs were shown to reduce HSP-72.
ADX-1612 is a selective inhibitor of heat shock protein 90, a molecular chaperone that controls the folding and activation of client proteins involved in DNA repair and cell division.
For increasing soluble expression of anti-CD20-huscFv, various approaches are used including co-expression with molecular chaperone, use of chemical chaperones and optimization of the culture conditions.
The Hsp70 is an ATP-dependent molecular chaperone mainly induced by heat or other abiotic stresses, whereas others are not heat inducible, and are present under normal growth conditions in some tissues (Su & Li 2008).
CRT is a molecular chaperone binding to calcium ions (Ca2+) that are located in the endoplasmic reticulum.
DNAJ-LP a type of molecular chaperone involved in proper folding of protein as well as showed abiotic stress response in plants.
(2) An in vitro study suggests that this protein acts as a molecular chaperone preventing thermal aggregation and forms a specific oligomeric structure.
Endogenous molecular chaperone function can be modulated pharmacologically with compounds that augment endogenous chaperone levels.
Yamazaki, "Prevention of aberrant protein aggregation by anchoring the molecular chaperone [alpha]B-crystallin to the endoplasmic reticulum," Biochemical and Biophysical Research Communications, vol.

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