Antipsychotic Drugs: Clozapine, Olanzapine, Perphenazine, Quetiapine, Thioridazine, Trifluoperazine, Loxapine, Methotrimeprazine, Molindone
A low-risk drug was prescribed to the rest of the patients (aripiprazole, ziprasidone, haloperidol, fluphenazine, molindone
, pimozide, or mesoridazine).
High-potency typical antipsychotic medications, such as phenothiazines, butyrophenones, and thioxanthenes are associated with hyperprolactinemia, whereas atypical antipsychotics, such as molindone
, clozapine, olanzapine, quetiapine, ziprasidone, and aripiprazole are thought to have little if any effect.
Antipsychotic Medications, Generic and Brand Names and Typical Tablet Dosage Generic Name Brand Name Tablet dosage range Atypical Risperidone Risperdal 1-3 mg Olanzapine Zyprexa 2.5-10 mg Clozapine Clozaril 25-100 mg Quetiapine Seroquel 25-200 mg Ziprasidone Geodon 20-60 mg Aripiprazole Abilify 5-15 mg High Potency Haloperidol Haldol 0.5-20 mg Typical Pimozide Orap 2 mg Fluphenazine Prolixin 2.5-10 mg Medium Potency Trifluoperazine Stelazine 1-10 mg Typical Perphenazine Trilafon 2-16 mg Thiothixene Navane 2-20 mg Loxapine Loxitane 5-50 mg Low Potency Molindone
Moban 5-100 mg Typical Mesoridazine Serentil 10-100 mg Thioridazine Mellaril 10-200 mg Chlorpromazine Thorazine 10-200 mg Adapted from Wilens (1999) and Li, Pearrow, & Jimerson (2010).
Some of the drugs given this label include prochlorperazine, haloperidol, loxapine, thioridazine, molindone
, thiothixene, pimozide, fluphenazine, and perphenazine.
For the study, published in the American Journal of Psychiatry, 116 children ages 8 to 19 were given molindone
, an older drug available as a generic, or a newer antipsychotic, either Lilly's Zyprexa, which generated $4.8 billion in sales in 2007, or J&J's Risperdal, with $4.7 billion in revenue.