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Related to monogenic: monogenic disease


1. Of or regulated by one gene or one of a pair of allelic genes.
a. Of or relating to monogenesis; monogenetic.
b. Of or relating to monogenism.

mon′o·gen′i·cal·ly adv.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


1. (Genetics) genetics of or relating to an inherited character difference that is controlled by a single gene
2. (Biology) (of animals) producing offspring of one sex
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌmɒn əˈdʒɛn ɪk)

1. bearing only male or only female forms.
2. pertaining to or being controlled by a single gene.
mon`o•gen′i•cal•ly, adv.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.monogenic - of or relating to an inheritable character that is controlled by a single pair of genesmonogenic - of or relating to an inheritable character that is controlled by a single pair of genes
genetic science, genetics - the branch of biology that studies heredity and variation in organisms
heritable, inheritable - capable of being inherited; "inheritable traits such as eye color"; "an inheritable title"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
One can use the technology to gain insightful information about drug sensitivity, family history of diseases, multifactorial or monogenic medical conditions.
Voyager's wholly-owned and partnered pipeline focuses on severe neurological diseases for which effective new therapies are needed, including Parkinson's disease, Huntington's disease, a monogenic form of ALS called SOD1, Friedreich's ataxia, Alzheimer's disease, and other neurodegenerative diseases related to defective or excess aggregation of tau and alpha-synuclein proteins in the brain.
The initiation of our Phase 1 clinical trial for Danon disease marked an important milestone for Rocket as we advanced the first AAV gene therapy for a monogenic heart failure syndrome into the clinic.
Sensorion is launching in the second half of 2019 two preclinical gene programmes aiming to correct hereditary monogenic forms of deafness including Usher Type 1 and deafness caused by a mutation of the gene encoding for Otoferlin.
The terms of the licences are predefined for two specific programmes aiming at correcting hereditary monogenic forms of deafness including Usher Type 1 and deafness caused by a mutation of the gene encoding Otoferlin.
In this study, a monogenic binary coding algorithm was considered to illustrate a good matching with local features through the analysis of monogenic signal theory and monogenic binary algorithm.
Keywords:Communicable disease, diabetes hearsay, IAPP, MODY, monogenic diabetes, non-communicable disease, prion diabetes, Type 1 diabetes, type 2 diabetes, viral diabetes.
In the coming years, most couples will check the embryos not only for chromosome diseases, but for monogenic diseases as well, thus having a positive impact on the fertility industry in the UAE," he said.
MRC4 receptor resistance - proopiomelanocortin (POMC) deficiency is also a rare cause of monogenic obesity but in these patients obesity begins in the first year of life and no autonomic dysfunction is described.
These techniques have been designed for a variety of purposes, including identification of embryos affected or carriers of monogenic diseases, identification of aneuploid embryos or selection of embryos with specific gender.
Classes and extracurricular activities also contributed to the development of my skills and abilities." At CUDOS 2018, Hasnah spoke about a case of childhood obesity that has a monogenic cause and how translational medicine can help.