In addition, metastatic melanoma will typically have a degree of cytologic atypia (the cells may be monomorphous
but atypical) and mitotic activity that is incongruous with a benign diagnosis.
Our patient's lesions were monomorphous
, and there were no comedones, pustules, or inflammatory papules characteristic of acne.
Histologically, PMAs display a marked myxoid matrix and monomorphous
bipolar cells that often radiate from vessels in an angiocentric pattern (Figure 4).
In addition, they are considered experts in their field and usually exert their influence only in that specific field (monomorphous
), although sometimes they can be influential in different areas of expertise as well (polymorphous; Katz & Lazarsfeld, 1955/2006).
Histology showed monomorphous
cells with serous-type clear cell cytoplasm, hyperchromatic nuclei, and partially acinus cell-like growth pattern of the parotid gland resembling acinic cell carcinoma.
Histologically, these tumors are characterized as monomorphous
oligoid tumor cells with round oval nuclei.
(A and B) The tumour is composed of monomorphous
spindle shaped cells in a prominent storiform pattern, infiltrating the hypodermal fat in a characteristic "honeycombing" pattern.
A complete medication history is important, as some medications can cause an abrupt onset of a monomorphous
On physical exam, lesions appear as monomorphous
, edematous papules and plaques that may develop vesicles.
Rippled pattern sebaceoma is characterized by dermal aggregation consisting of monomorphous
, small, basaloid, sebaceous germinative cells.
The pruritic rash usually consists of acute-onset monomorphous
, flat-topped or dome-shaped red-brown papules and papulovesicles, one to 10 mm in size, located symmetrically on the face (FIGURE 6), the extensor surfaces of the arms and legs, and, less commonly, the buttocks.
Microscopically, the lesion consisted of a cystic wall lined by two or more rows of sweat-duct-like epithelium, with monomorphous
cubic cells characterized by a small, central nucleus and without cytologic atypia (Figure 3).