Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to monosomic: trisomic, Nullisomic


1. A chromosome having no homologue, especially an unpaired X chromosome.
2. A single ribosome.

mon′o·so′mic (-sō′mĭk) adj.
mon′o·so′my n.


(ˌmɒn əˈsoʊ mɪk)

having one less than the usual diploid number of chromosomes.
Mentioned in ?
References in periodicals archive ?
These unstable chromosomes can also lead to ring chromosome loss, producing monosomic cells, which may or may not be viable.
Extensive cytogenetic studies of clonality following interferon-alpha therapy in chronic myeloid leukemia occurring in monosomic cells in a patient with Turner syndrome mosaic".
It is unknown whether recommendations for interpreting the FDA-approved control probe in these apparent monosomic cases can be extrapolated to alternate probes.
White Matter Aberrations in Prepubertal Estrogen-Naive Girls with Monosomic Turner Syndrome.
Lr46/Yr29: A slow rusting gene identified in the cultivar Pavon and was found located on chromosome 1B by crossing with a monosomic series of adult plant leaf rust susceptible cultivar Lal Bahadur (Singh et al.
Altman (1991) Identification of four Gossypium sturtianum monosomic alien addition derivatives from a backcrossing program with G.
A monosomic analysis of Russian wheat aphid resistance in the common wheat PI 294994.
These other cases had similar deletions in either the p or q arms, and so were monosomic for only one end of chromosome 9, in contrast to our patient who was monosomic for both ends of chromosome 9.
This hypothesis has gained support in recent years given that a great number of X chromosome genes escape inactivation, suggesting that healthy women experience a different effect linked to the X compared, both to men and to patients diagnosed with TS, which are monosomic for the X (6) chromosome.
In the present case, a trivalent configuration in metaphase I of meiosis could have resulted in a monosomic or trisomic condition.
destructor from the USA populations was karyotyped (Stuart and Hatchett 1988) and the authors found that female somatic cells have two pairs of autosomes and two pairs of sex chromosomes (2n = 8), while male somatic cells have two pairs of autosomes and two monosomic sex chromosomes (2n - 2 = 6).
We have developed and released 17 disomic, chromosome substitution (CS-B) lines through hypoaneuploid-based backcross chromosome substitution, using as recurrent parent a previously developed monosomic or monotelodisomic near-isogenic backcross derivative of TM-1.