The blocking of the several biological pathways allows bispecific antibodies to display a synergistic effect, which is unachievable with a mixture of monospecific
Merus is developing MCLA-145 as part of a collaboration entered into with Incyte in December 2016 to potentially develop and commercialize up to 11 bispecific and monospecific
antibodies from the Merus Biclonics platform.
In addition, Zymeworks' Azymetric platform enables the transformation of monospecific
antibodies into bispecific antibodies, giving the antibodies the ability to simultaneously bind two different targets.
Eremionycha is a monospecific
genus, occurring exclusively in Brazil in the states of Bahia, Espirito Santo and Santa Catarina.
During September-October 2016, we collected 541 combined oral-pharyngeal and cloacal swab samples from hunter-harvested waterfowl (Anseriformes spp.) and 401 environmental fecal samples from monospecific
flocks of either emperor geese (Chen canagica) or glaucous-winged gulls (Larus glaucescens) within and around Izembek NWR.
Transforming native habitats into monospecific
(single species) forests that consist only of popcorn trees," said Todd Matthews, Urban Forestry and Forest Health Coordinator.
While it has become rather quiet around the avian antibodies, much of modern research is now inconceivable without the in vitro production of monoclonal antibodies and it has become clear that fully animal-free recombinant antibodies are not only ethically but also scientifically superior to antibodies produced by hybridomas, as the latter are not always monospecific
These cells have two main characteristics, production of uniform, monospecific
antibodies (mAbs) that originate from the B-cell and immortality that comes from the myeloma cell line.
Identification and biotyping of the putative Brucella isolates were done by assessing colony morphology, biochemical reactions, C[O.sub.2] requirement, production of H2S, growth in the presence of the dyes thionine and fuchsine, reaction with monospecific
antisera (A, M, and R), and phage lysis (Wb, Tb, and F25) .