Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to monovalent: monovalent vaccine


1. Immunology
a. Containing antigens from a single strain of a microorganism or virus. Used of a vaccine or serum.
b. Having only one site of attachment. Used of an antibody or antigen.
2. Chemistry Univalent.

mon′o·va′lence, mon′o·va′len·cy n.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.


(Chemistry) chem
a. having a valency of one
b. having only one valency
ˌmonoˈvalence, ˌmonoˈvalency n
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014


(ˌmɒn əˈveɪ lənt)

a. containing only one kind of antibody.
b. pertaining to an antibody fragment with one antigen-binding site.
mon`o•va′lence, mon`o•va′len•cy, n.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.monovalent - containing only one kind of antibody
immunology - the branch of medical science that studies the body's immune system
polyvalent - containing several antibodies each capable of counteracting a specific antigen; "a polyvalent vaccine"
2.monovalent - having a valence of 1
chemical science, chemistry - the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions
multivalent, polyvalent - having more than one valence, or having a valence of 3 or higher
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
References in periodicals archive ?
Global Pediatric Vaccines Market Research Report Show the information by Type Monovalent Vaccines, Multivalent Vaccines, Technology Attenuated, Toxoid, Conjugate, Inactivated & Subunit, Recombinant), Disease Indication Hepatitis, Pneumococcal Disease, DTP, Dengue, Influenza, Human Papilloma Virus, Meningococcal Disease, Polio, Rotavirus - Global Forecast Till 2023
Formulation of vaccines: The gel based monovalent, bivalent and trivalent (combined) PPR; FMDO and CCPP vaccines were prepared (OIE, 2008).
The patent, entitled 'Monovalent Metal Cation Dry Powders for Inhalation', protects formulations that includes an anti-fungal agent with iSPERSE formulations.
Anti-venom type segment was divided into monovalent and polyvalent anti-venom.
"In response to these studies in non-human primates, our next clinical trial in humans will compare subcutaneous with intramuscular deliveries of protein boosts and whether the simpler monovalent CD4-induced gp120 is as effective at eliciting the desired antibody responses as the bivalent protein boost," said Dr.
Although the monovalent vaccine is generally safe with a favourable benefit-risk ratio, it is associated with the potentially serious, albeit rare, adverse effect of intestinal intussusception.3 Intussusception refers to intestinal obstruction caused by telescoping of a bowel segment into its adjacent distal segment, and is the commonest cause of acute abdomen in children.
'We have also received 2,000 monovalent ASV produced by Micropharm Ltd, United Kingdom, solely for carpet vipers, the commonest snakes in Nigeria,'' Durfa told the News Agency of Nigeria (NAN), on Sunday in Jos.
Discovered and engineered using Numab's proprietary ?cap technology and MATCH platform, ND021 is a late-preclinical-stage, monovalent, tri-specific antibody-based molecule (scMATCH3) that simultaneously targets PD-L1, 4-1BB, and HSA.
In case your child has already been exposed to someone infected with measles, it is best to get a measles vaccine such as Monovalent Measles (MM), Measles and Rubella (MR), or Measles, Mumps, and Rubella (MMR) as post-exposure prophylaxis within 72 hours.
The highest odds ratios were among women who had been vaccinated in the 2010-2011 season and had also been vaccinated with monovalent pandemic HlNl vaccine in the 2009-2010 season (aOR, 32.5; 95% CI, 2.9-359.0).
Indeed, two inactivated monovalent enterovirus-A71 (EV-A71) vaccines are now licensed in China, and a third is in phase 3 clinical trials.