Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to monovalent: monovalent vaccine


1. Immunology
a. Containing antigens from a single strain of a microorganism or virus. Used of a vaccine or serum.
b. Having only one site of attachment. Used of an antibody or antigen.
2. Chemistry Univalent.

mon′o·va′lence, mon′o·va′len·cy n.


(Chemistry) chem
a. having a valency of one
b. having only one valency
ˌmonoˈvalence, ˌmonoˈvalency n


(ˌmɒn əˈveɪ lənt)

a. containing only one kind of antibody.
b. pertaining to an antibody fragment with one antigen-binding site.
mon`o•va′lence, mon`o•va′len•cy, n.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Adj.1.monovalent - containing only one kind of antibody
immunology - the branch of medical science that studies the body's immune system
polyvalent - containing several antibodies each capable of counteracting a specific antigen; "a polyvalent vaccine"
2.monovalent - having a valence of 1
chemical science, chemistry - the science of matter; the branch of the natural sciences dealing with the composition of substances and their properties and reactions
multivalent, polyvalent - having more than one valence, or having a valence of 3 or higher
References in periodicals archive ?
The highest odds ratios were among women who had been vaccinated in the 2010-2011 season and had also been vaccinated with monovalent pandemic HlNl vaccine in the 2009-2010 season (aOR, 32.
Indeed, two inactivated monovalent enterovirus-A71 (EV-A71) vaccines are now licensed in China, and a third is in phase 3 clinical trials.
Antibody response of the birds to either immunogen of monovalent vaccines (O-MG and O-IV) was not significantly different (P>0.
A monovalent brine heat pump allows the building to be heated in winter and cool in summer.
When they vaccinated mice with either the bivalent or monovalent vaccine (both with genetically identical human HA proteins), they found equal immune responses across the board.
7) Two recombinant monovalent vaccines were simultaneously developed by SmithKline Beecham (LYMErix) and Pasteur Merieux Connaught (ImmuLyme) in the 1990s.
All elements with an atomic number of 13 (aluminum) or greater are measured simultaneously, including biologically important monovalent ions (e.
HepB vaccine doses subsequent to the monovalent HepB vaccine birth dose are administered as either monovalent or combination vaccine (1).
2,] which are identical or different, represent a monovalent hydrocarbon-based group chosen from alkyls, which are linear or branched, cycloalkyls or aryls, having from 1 to 18 carbon atoms; [R.
Producing multi-strain, or multivalent, vaccines that could protect against different types of Ebola and other haemorrhagic fevers will be more time-consuming than making today's monovalent shots, but it is by no means impossible.
They include inactivated seasonal and pandemic influenza, mono- and combined meningococcal polysaccharide and conjugated vaccines, tetanus toxoid and acellular pertussis combination vaccines, as well as monovalent or combined rubella, oral poliomyelitis virus and yellow fever vaccines.