gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus.
Thus, parafibromin integrates and converts signals conveyed by these morphogen
pathways into appropriate transcriptional outputs in a tyro sine phosphorylation/dephosphorylation-regulated manner.
This pattern of expression suggests a role for IGF-I as a sebaceous mitogen and morphogen
BMP-2 is a key morphogen
for transcriptional activation of osteoblast lineage commitment and hence influence bone metabolism and strength (Banerjee et al.
A symbiont-derived morphogen
is tracheal cytotoxin (TCT), a fragment of the bacterial envelope component peptidoglycan, which works in synergy with a second envelope component, lipopolysaccharide (LPS), to trigger a morphogenesis nearly indistinguishable from the developmental program that occurs naturally (Koropatnick et al.
Mice injected with these MPs show improved acetylcholine-evoked relaxation of the aorta and induce NO production directly by the hedgehog morphogen
pathway, which involves PI3K and protein kinase B (Akt) (29).
Citation: "A microparticle approach to morphogen
delivery within pluripotent stem cell aggregates"; Andres M.
The research does not nix the theory - called the morphogen
theory - but science may now have a hypothetical tiger by the tail as they try to figure out this aspect of how Nature works.
A tissue-specific enhancer confers Pit-1-dependent morphogen
inducibility and autoregulation on the Pit-1 gene.
Although the detailed mechanism of STS action as a neurogenic morphogen
remains unclear, it seems that it is associated with the inhibition of some protein kinases which may contribute to neurite outgrowth .
Generation of a novel wing colour pattern by the Wingless morphogen
Generation and interpretation of morphogen